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Computational pathology literature registry

This is the structured source behind the computational-pathology lists in My Library. It makes year, publication state, route membership, official artifacts, and the last metadata-check date visible in one place.

Coverage cutoff: 2 September 2026. “Current” means that the maintained routes and frontier searches were reviewed through that date. It does not mean that every paper ever written is included. Recent preprints are labeled separately from peer-reviewed work, and venue-accepted papers remain “accepted” until a proceedings record is available.

342 unique computational-pathology papers10 detailed research routesRoutes reviewed through October 2, 2026

Showing 342 of 342 records.

  1. self-supervised learning · foundation encoder · evaluation · foundation model benchmark · out-of-domain evaluation

    Metadata checked

  2. 2026arXivPreprint

    A Generative Foundation Model for Multimodal Histopathology

    Jinxi Xiang, Mingjie Li, Siyu Hou, Yijiang Chen, Xiangde Luo, Yuanfeng Ji, Xiang Zhou, Ehsan Adeli, Akshay Chaudhari, Curtis P. Langlotz, Kilian M. Pohl, and Ruijiang Li

    L3

    generative / virtual pathology · spatial / molecular · pathology VLM · MuPD · multimodal pathology diffusion · virtual staining · missing-modality synthesis

    Metadata checked

  3. 2026Cancer ResearchPeer reviewed

    A Magnification Alignment Framework Enables Computation- and Communication-Efficient Computational Pathology

    Chu Han, Bingchao Zhao, Tianpeng Deng, Jingqi Huang, Fangfang Liu, Jiatai Lin, Shanshan Lyu, Longfei Wang, Cheng Lu, Changhong Liang, Hannah Y. Wen, Zhenwei Shi, Xiaojing Guo, and Zaiyi Liu

    L3

    Peer-reviewed journal article 86(12):3060–3073.

    knowledge distillation / model transfer · MIL / WSI · WSI engineering · self-supervised learning · MAG-GLTrans · magnification alignment · registered field of view · low-magnification deployment · telepathology efficiency

    Official artifacts: Author manuscript · Official code

    Metadata checked

  4. evaluation · spatial / molecular · MIL / WSI · conformal prediction · survival analysis · censoring · risk guarantees

    Metadata checked

  5. pathology VLM · MIL / WSI · active navigation · tissue-aware reasoning · visual grounding

    Metadata checked

  6. spatial / molecular · evaluation · HEX · virtual spatial proteomics · biomarker discovery

    Metadata checked

  7. 2026arXivPreprint

    ALICE: Learning a General-Purpose Pathology Foundation Model from Vision, Vision-Language, and Slide-Level Experts

    Jiawen Li, Tian Guan, Huijuan Shi, Xitong Ling, Mingxi Fu, Anjia Han, Chao He, and Yonghong He

    L3

    foundation encoder · agglomerative distillation · multi-teacher · foundation model · knowledge distillation / model transfer

    Official artifacts: Code and models

    Metadata checked

  8. 2026arXivPreprint

    An end-to-end-trained vision-language model for native-language prostate pathology report generation

    Christian Grashei, Fabian Gülhan, Maximilian Legnar, Fabian Stögbauer, Cleo-Aron Weis, Carolin Mogler, and Peter Schüffler

    L3

    arXiv v1 preprint submitted 24 August 2026; no peer-reviewed record, public training code, model weights, or paired clinical dataset release was verified by the review cutoff.

    pathology VLM · MIL / WSI · evaluation · prostate biopsy · native-language report generation · German clinical text · slide-level VLM · end-to-end training · automated report pairing

    Metadata checked

  9. evaluation · prospective observational study · prostate biopsy · workflow

    Metadata checked

  10. Submitted 2026-07-14; retain preprint status and evaluate its audit protocol independently.

    pathology VLM · evaluation · data leakage · benchmark provenance · multimodal WSI

    Metadata checked

  11. 2026MICCAIPeer reviewed

    Benchmarking Pathology Foundation Models for Spatial Domain Understanding

    Bokai Zhao, Yiyang Zhang, Yuanchi Zhu, Hanqing Chao, Long Bai, Tai Ma, Minfeng Xu, Ming Song, and Tianzi Jiang

    L3

    MICCAI 2026 chapter, LNCS 16895, pages 35–45, first online 25 September 2026; the volume imprint says 2027. Review uses the inspected publisher PDF. The 42 slides comprise 12 expert-annotated DLPFC slides and 30 slides assessed using transcriptomic clustering proxies. The linked public repository is a prepared-results dashboard, not a verified end-to-end benchmark implementation.

    evaluation · foundation encoder · spatial / molecular · cell / tissue modeling · SpaPath-Bench · spatial domain identification · paired histology and spatial transcriptomics · benchmark · proxy-reference evaluation

    Official artifacts: Publisher full chapter · Official MICCAI open-access record · Official accepted manuscript · Author results dashboard · Dashboard repository and documented limits

    Metadata checked

  12. 2026arXivPreprint

    Benchmarking Vision-Language Models for Automated Pathology Diagnosis and Report Generation

    Yumi Lee, Harim Oh, Hyoryung Kim, Minji Kim, Eunsu Kim, Hyeseong Lee, Junya Fukuoka, Andrey Bychkov, Jijgee Munkhdelger, Rajiv Kumar Kaushal, Ayushi Sahay, Rajni Yadav, Bharathi Prabakaran, Sulen Sarioglu, Serdar Balcı, Ilknur Turkmen, Yuri Tolkach, Christian Harder, Julian Westerdorf, Reinhard Buettner, Audun Ljone Henriksen, Sepp De Raedt, Byung Hyun Lee, Sungjin Lim, Joohoon Lee, Gwanghyun Kim, Se Young Chun, Suryakant Singh, Saarthak Kapse, Prateek Prasanna, Kyung A Kim, Yousun Kang, Sehwan Yoo, Sungman Hong, Shubham Innani, Michael Feldman, Spyridon Bakas, Ujjwal Baid, Prasad Dutande, Suhas Gajare, Bhakti Baheti, Serkan Sökmen, Ece Tuğba Cebeci, Ahmet Halıcı, Musa Balcı, Kardelen Peçenek, Srividhya Sainath, Kyongseok Jang, Messi H. J. Lee, Noorul Wahab, Bodong Du, Jiaming Zhang, Qixiang Zhang, Jang-Hwan Choi, and Sangjeong Ahn

    L3

    arXiv v1 submitted 1 September 2026 reports the results of the MICCAI REG 2025 challenge. No final peer-reviewed proceedings or journal record was verified on 2 September 2026. The approximately 10,500 institutional WSI-report pairs are not a generally downloadable public dataset; the released repositories expose benchmark information and team artifacts.

    pathology VLM · evaluation · MIL / WSI · robustness / domain shift / privacy · REG 2025 · pathology report generation · WSI-report pairs · Pan-Asia cohort · clinical VLM benchmark · numeric hallucination

    Official artifacts: Official challenge repository · Official winning-system repository · Official challenge site

    Metadata checked

  13. cell / tissue modeling · foundation encoder · evaluation · mitotic figure detection · dense transfer · cross-species pathology

    Official artifacts: Official code

    Metadata checked

  14. 2026arXivPreprint

    Beyond Counts: A Distributional Robustness Margin For Pathology Foundation Models

    Clément Grisi, Jeroen van der Laak, and Geert Litjens

    L3

    foundation encoder · evaluation · distributional robustness · cell composition · foundation-model evaluation · optimal transport

    Metadata checked

  15. 2026CVPRPeer reviewed

    Beyond Pixel Simulation: Pathology Image Generation via Diagnostic Semantic Tokens and Prototype Control

    Minghao Han, Yichen Liu, Yizhou Liu, Zizhi Chen, Jingqun Tang, Xuecheng Wu, Dingkang Yang, and Lihua Zhang

    L3

    generative / virtual pathology · pathology VLM · evaluation · UniPath · diagnostic semantic tokens · prototype control · flow matching

    Official artifacts: Author preprint · Official code and data

    Metadata checked

  16. 2026arXivPreprint

    Beyond Relevance: Bayesian Evidence Acquisition for Agentic Whole-Slide Image Reasoning

    Bryan Wong, Xun Xu, Huazhu Fu, Nancy F. Chen, and Mun Yong Yi

    L3

    pathology VLM · MIL / WSI · BEACON · Bayesian evidence acquisition · agentic WSI reasoning · expected information gain

    Official artifacts: Official code

    Metadata checked

  17. foundation encoder · MIL / WSI · spatial / molecular · adaptive regions · molecular guidance · slide foundation model · self-supervised learning

    Metadata checked

  18. The official implementation describes a NeurIPS 2026 submission; no acceptance or proceedings record was available when checked on 2026-08-10.

    cell / tissue modeling · foundation encoder · CellDETR · cell representation learning · Deformable DETR · histopathology · contrastive pretraining · detection / segmentation

    Official artifacts: Official code

    Metadata checked

  19. 2026Computer Methods and Programs in BiomedicinePeer reviewed

    CellViT++: Energy-Efficient and Adaptive Cell Segmentation and Classification Using Foundation Models

    Hörst et al.

    L3

    cell / tissue modeling · CellViT++ · efficient adaptation · foundation model

    Metadata checked

  20. Peer-reviewed journal article, volume 135, article 111204. The weakly supervised model uses 5×, 10×, and 20× streams and retains their cross-attention fusion at inference; it is not a low-magnification-only student. No official artifact was verified on 2026-09-02.

    MIL / WSI · WSI engineering · evaluation · CMA-MIL · cross-magnification attention · discriminative attribute scoring · renal cell carcinoma · whole-slide MIL

    Metadata checked

  21. 2026arXivPreprint

    Computationally Efficient Pathology Segmentation using Knowledge Distillation from Foundation Models

    Jiaqi Lv, Yijie Zhu, Saki Okada, Maxwell Stanley Renna, Robert Goldin, Stefan Antonowicz, and Shan E Ahmed Raza

    L3

    arXiv v1 (2026-09-03), submitted to Medical Image Analysis according to the authors, not accepted. Verified methods and selected results on 2026-10-02. TIAToolbox is the stated release destination; availability of these exact weights was not independently confirmed. Patch-throughput measurements are not end-to-end WSI latency.

    cell / tissue modeling · foundation encoder · WSI engineering · knowledge distillation / model transfer · detection / segmentation · Virchow2 · segmentation knowledge distillation · pixel and feature transfer · SegFormer · EUNet · efficient WSI processing

    Official artifacts: Versioned manuscript · TIAToolbox — stated release destination

    Metadata checked

  22. 2026MIDLPeer reviewed

    ConStruct: Structural Distillation of Foundation Models for Prototype-Based Weakly Supervised Histopathology Segmentation

    Khang Le, Ha Thach, Anh M. Vu, Trang T. K. Vo, Han H. Huynh, David Yang, Minh H. N. Le, Thanh-Huy Nguyen, Akash Awasthi, Chandra Mohan, Zhu Han, and Hien Van Nguyen

    L3

    Peer-reviewed MIDL 2026 proceedings, PMLR 315:2893–2905; official record verified 2026-10-02.

    cell / tissue modeling · pathology VLM · knowledge distillation / model transfer · ConStruct · structural knowledge distillation · CONCH · SegFormer · weakly supervised segmentation · text-guided prototypes

    Official artifacts: Official proceedings PDF · Official implementation

    Metadata checked

  23. MIL / WSI · cross-bag augmentation · contrastive learning · MIL

    Metadata checked

  24. The manuscript states that code will be released upon publication; no released implementation was claimed when checked on 2026-08-08.

    pathology VLM · foundation encoder · evaluation · CorePath · core needle biopsy · report generation · conformal risk control

    Metadata checked

  25. 2026Engineering Applications of Artificial IntelligencePeer reviewed

    Cross-Stain Knowledge Distillation for Low-Cost Lung Cancer Programmed Death Ligand-1 Assessment With Multi-Granularity Multiple Instance Learning

    Yi Shi, Chong Ge, Fang Zhao, Anli Zhang, Ao Li, Haibo Wu, and Minghui Wang

    L3

    Peer-reviewed journal article, volume 167, article 113762. IHC is privileged teacher information during training; deployment uses the H&E student, but its macro- and micro-granularity branches remain. No official code or model release was verified on 2026-09-02.

    knowledge distillation / model transfer · MIL / WSI · spatial / molecular · WSI engineering · evaluation · CroSMuG · cross-stain distillation · PD-L1 assessment · privileged IHC teacher · multi-granularity MIL

    Metadata checked

  26. 2026arXivPreprint

    DaX: Learning General Pathology Representations Across Scales

    Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, and Minfeng Xu

    L3

    self-supervised learning · foundation encoder · cross-scale SSL · continuous magnification · DINOv3

    Official artifacts: Code

    Metadata checked

  27. 2026arXivPreprint

    Decoupled I/O-Dominant Pipelines for Large-Scale Whole-Slide Image Embedding Extraction

    Mayanka Chandrashekar, Xi Zhang, Ethan Seefried, Tirthankar Ghosal, John Gounley, and Heidi Hanson

    L3

    arXiv v1 systems preprint submitted 27 August 2026; no peer-reviewed version, official implementation, or reusable deployment package was verified by the review cutoff.

    WSI engineering · evaluation / reproducibility · WSI embedding extraction · I/O bottleneck · decoupled pipeline · distributed inference · vector database · systems scaling

    Metadata checked

  28. spatial / molecular · evaluation · TAILORx · recurrence · treatment benefit

    Metadata checked

  29. pathology VLM · open pipeline · HISTAI-Instruct · whole-slide copilot

    Official artifacts: Code, data, and model

    Metadata checked

  30. 2026Journal of Pathology InformaticsPeer reviewed

    Deployment of AI-driven automated quality control of whole-slide images in a large tertiary cancer center

    Kaitlyn Gelfant et al.

    L3

    WSI engineering · evaluation · quality control · operational deployment · workflow

    Metadata checked

  31. 2026TMLRPeer reviewed

    DINOv3

    Meta AI et al.

    Research

    self-supervised learning · DINOv3 · scaling · visual representation learning

    Metadata checked

  32. 2026arXivPreprint

    Do Pathology Vision-Language Models Truly See Pathology?

    Chengyang Zhang et al.

    L3

    pathology VLM · PathBind · visual binding · multimodal evaluation

    Metadata checked

  33. MIL / WSI · hypergraph · feature scarcity · WSI

    Metadata checked

  34. 2026ECCV eXCV WorkshopAccepted · proceedings pending

    EXPOSE: Explainable and Domain-Robust Embeddings from Pathology Vision Foundation Models using Sparse Autoencoders

    Anja Witte, Maximilian Lennartz, Jan Baumbach, Guido Sauter, Stefan Bonn, Patrick Fuhlert, and Marina Zimmermann

    L3

    Independently verified on the official eXCV 2026 Proceedings Track list, not ECCV main conference. Scientific review uses arXiv:2608.28191v1; a final typeset proceedings version was not verified. Evaluation is prostate tissue-microarray spots, not a whole-slide benchmark, and includes a thin-section failure case.

    robustness / domain shift / privacy · evaluation · interpretability / attribution · SAE · EXPOSE · sparse autoencoders · domain feature masking · H0-mini · TMA · domain robustness

    Official artifacts: Official workshop accepted-paper list · Author implementation · Versioned full manuscript and appendix

    Metadata checked

  35. MIL / WSI · end-to-end WSI · feature bridging · single GPU

    Metadata checked

  36. spatial / molecular · FineST · spatial transcriptomics · single-cell

    Metadata checked

  37. 2026ECCVAccepted · proceedings pending

    From Multi-Resolution Cells to Gigapixel Whole Slide Images Foundation Model for Computational Pathology

    Basit Alawode, Moshira Ali Abdalla, Dwarikanath Mahapatra, Muhammad Muzammal Naseer, and Sajid Javed

    L3

    ECCV 2026 acceptance is now verified by official poster 4422, superseding the preprint-only catalog status. A Springer version of record was not verified on 2026-09-12; the existing review remains tied to its declared manuscript revision.

    foundation encoder · self-supervised learning · MIL / WSI · MRPT · multi-resolution foundation model · cross-resolution attention · hierarchical SSL

    Official artifacts: Official ECCV 2026 poster · Conference manuscript

    Metadata checked

  38. 2026MICCAIPeer reviewed

    From Patches to Patients: A Study of the Tile-to-Slide Performance Transferability in Digital Pathology

    Sofiène Boutaj, Leo Fillioux, Maria Vakalopoulou, Stergios Christodoulidis, and Pierre Marza

    L3

    MICCAI 2026 chapter, LNCS 16891, pages 149–159; publisher first-online date is in September 2026, although the volume copyright/bibliographic imprint says 2027. Review uses the inspected publisher PDF, not only arXiv:2606.10778. Across-encoder rank correlation supports shortlisting, not guaranteed selection of the best model for a new clinical cohort.

    evaluation · foundation encoder · MIL / WSI · WSI engineering · tile-to-slide transfer · encoder selection · THUNDER · PathoBench · ABMIL · rank correlation

    Official artifacts: Publisher full chapter · Official MICCAI open-access record · Official accepted manuscript · Earlier arXiv manuscript

    Metadata checked

  39. 2026Company technical reportTechnical report

    GenBio-PathFM: A State-of-the-Art Foundation Model for Histopathology

    Saarthak Kapse, Mehmet Aygün, Elijah Cole, Emma Lundberg, Le Song, and Eric P. Xing

    L3

    Public technical report and weights; no peer-reviewed version was located by 2026-07-27.

    self-supervised learning · foundation encoder · JEDI · JEPA · morphology curation

    Official artifacts: Code · Model

    Metadata checked

  40. 2026ACM MultimediaAccepted · proceedings pending

    Gene Ontology-Guided Hierarchical Spatial Gene Expression Prediction from Histopathology Images

    Zhiwen Xu, Xiaoming Yan, Chengkun Wu, Juan Chen, Haoang Chi, and Liyang Xu

    L3

    The arXiv record reports acceptance at ACM Multimedia 2026. The proceedings record was not yet available when checked on 2026-08-08.

    spatial / molecular · cell / tissue modeling · MSGR · spatial gene expression · Gene Ontology · hierarchical graph learning

    Official artifacts: Official code

    Metadata checked

  41. Version 2 dated 2026-07-22; author-reported performance remains provisional.

    self-supervised learning · foundation encoder · MIL / WSI · spatial / molecular · efficient foundation model · distillation · tumor microenvironment · knowledge distillation / model transfer

    Metadata checked

  42. 2026MICCAIPeer reviewed

    Harnessing Adversarial Distillation to Customise Debiased, Disease-Specific Pathology Foundation Models for Breast Cancer

    Zhiwei Chen, Yang Hu, Yuxiang Xiao, Yakun Ju, Tianyang Zhang, Yingxue Xu, Wei Li, Hao Chen, Jens Rittscher, and Kaixiang Yang

    L3

    Official MICCAI 2026 proceedings record and accepted-version open-access PDF verified 2026-10-02; Springer DOI and pagination remain pending.

    foundation encoder · self-supervised learning · evaluation · SmartStu · adversarial distillation · disease-specific foundation model · debiasing · knowledge distillation / model transfer

    Official artifacts: Official code · Official MICCAI 2026 proceedings · Official accepted-version PDF

    Metadata checked

  43. spatial / molecular · HESpotEx · gene expression · spatial graph

    Metadata checked

  44. 2026WACVPeer reviewed

    HistoMILKD: A Multiple Instance Learning based Multi-Teacher Knowledge Distillation Framework for Whole Slide Image Classification

    Mayur Mallya, Ali Khajegili Mirabadi, Hossein Farahani, and Ali Bashashati

    L2–L3

    MIL / WSI · knowledge distillation · multi-teacher · foundation encoders · knowledge distillation / model transfer

    Official artifacts: Code

    Metadata checked

  45. pathology VLM · multimodal in-context learning · retrieval · report generation

    Metadata checked

  46. Peer-reviewed open-access journal article 16:20721. A MobileViT-XS is sequentially adapted from 40× through 400× using the previous checkpoint as teacher; BreakHis consists of biopsy images rather than WSIs, and the same-capacity teacher/student design targets retention rather than model compression.

    knowledge distillation / model transfer · cell / tissue modeling · evaluation · robustness / domain shift / privacy · KDT-ViT · progressive cross-magnification learning · MobileViT · BreakHis · patch classification

    Official artifacts: Open-access article

    Metadata checked

  47. pathology VLM · foundation encoder · knowledge graph · hierarchical semantics · zero-shot diagnosis

    Official artifacts: Code · Model

    Metadata checked

  48. 2026npj ImagingCorrected

    Label-free whole slide virtual multi-staining using dual-excitation photon absorption remote sensing microscopy

    James E. D. Tweel, Benjamin R. Ecclestone, James A. Tummon Simmons, and Parsin Haji Reza

    L3

    Author correction published 10 April 2026; the version-of-record page is the canonical updated article.

    generative / virtual pathology · evaluation · whole-slide virtual staining · PARS microscopy · multi-staining · RegGAN · label-free histology

    Official artifacts: Public held-out WSI pairs (BioImage Archive)

    Metadata checked

  49. Official MICCAI 2026 proceedings record and accepted-version open-access PDF verified 2026-10-02; this supersedes the prior preprint classification. Springer DOI remains pending.

    knowledge distillation / model transfer · foundation encoder · pathology VLM · MIL / WSI · LaGuadia · language-guided distillation · multi-teacher transfer · pathology foundation models · multimodal student

    Official artifacts: Official code · Official MICCAI 2026 proceedings · Official accepted-version PDF

    Metadata checked

  50. arXiv preprint first submitted in 2025 and substantially revised as v2 on 24 August 2026; no peer-reviewed version or official implementation was verified by the review cutoff.

    MIL / WSI · WSI engineering · pathology VLM · image–text representation · LanGuSTE · coarse-to-fine patch selection · cross-scale visual prompt tuning · LLM-derived concepts · 5× to 20× selection

    Metadata checked

  51. 2026Nature MethodsPeer reviewed

    LazySlide: accessible and interoperable whole-slide image analysis

    Yimin Zheng, Ernesto Abila, Eva Chrenková, Iva Buljan, Juliane Winkler, and André F. Rendeiro

    L1–L2

    WSI engineering · spatial / molecular · WSI framework · interoperability · SpatialData

    Metadata checked

  52. L3

    spatial / molecular · foundation encoder · spEMO · spatial multi-omics · multimodal foundation model

    Metadata checked

  53. Official MICCAI 2026 proceedings record and accepted-version open-access PDF verified 2026-10-02. Springer DOI and pagination remain pending; do not invent either.

    MIL / WSI · WSI engineering · cross-resolution distillation · low-resolution MIL · efficient WSI inference · knowledge distillation · knowledge distillation / model transfer

    Official artifacts: Official code · Official MICCAI 2026 proceedings · Official accepted-version PDF

    Metadata checked

  54. 2026Medical Image AnalysisPeer reviewed

    M2OTCA: Multiple-Magnification Optimal Transport-Based Cross-Attention Learning for Whole Slide Image Classification

    Zhonghang Zhu, Erik Meijering, and Liansheng Wang

    L3

    Peer-reviewed journal article, volume 112, article 104082. Region structural prototypes reduce the cost of optimal transport across 5×, 10×, and 20×; all three magnifications feed magnification-specific predictions and remain part of inference. No official artifact was verified on 2026-09-02.

    MIL / WSI · WSI engineering · evaluation · M2OTCA · optimal transport · cross-magnification cross-attention · region structural prototypes · whole-slide MIL

    Official artifacts: PubMed record

    Metadata checked

  55. pathology VLM · evaluation · retrieval augmentation · differential diagnosis · melanocytic lesions

    Official artifacts: Code

    Metadata checked

  56. 2026ICLRPeer reviewed

    Mixture of Mini Experts: Overcoming the Linear Layer Bottleneck in Multiple Instance Learning

    Daniel Shao, Joel Runevic, Richard J. Chen, Drew F. K. Williamson, Ahrong Kim, Andrew H. Song, and Faisal Mahmood

    L3

    MIL / WSI · MAMMOTH · feature transformation · mixture of experts

    Official artifacts: Code

    Metadata checked

  57. 2026CVPRPeer reviewed

    MLLM-HWSI: A Multimodal Large Language Model for Hierarchical Whole Slide Image Understanding

    Basit Alawode, Arif Mahmood, Muaz Khalifa Al Radi, Shahad Albastaki, Asim Khan, Muhammad Bilal, Moshira Ali Abdalla, Mohammed Bennamoun, and Sajid Javed

    L3

    pathology VLM · hierarchical WSI · multiscale grounding · multimodal LLM

    Metadata checked

  58. 2026NeurIPSAccepted · proceedings pending

    Modeling Whole-Slide Images as Dynamic Tumor Microenvironment Fields

    Lei Wu, Jiashuai Liu, Di Zhang, Zhangpeng Gong, Yingkang Zhan, Yi Niu, Jiusong Ge, Chunze Yang, Kai Yi, Mireia Crispin-Ortuzar, Chen Li, and Zeyu Gao

    L3

    Accepted as a NeurIPS 2026 poster: official conference program event 149764 matches the exact title and 12 authors, checked 2026-10-08. Final proceedings were not verified; review uses arXiv v1 (2026-09-28). Official method code is available under a noncommercial research license, but does not include the WSI feature-extraction pipeline. Tissue-tile pixel size, extraction magnification/MPP, and image preprocessing remain unreported in the inspected paper and release.

    MIL / WSI · pathology VLM · spatial / molecular · TMEvolve · adaptive region modeling · reaction-diffusion-inspired graph learning · concept-guided boundary flux · survival prediction · gene expression prediction

    Official artifacts: Reviewed manuscript and supplement (v1) · Author publication and acceptance statement · Official NeurIPS 2026 poster · Official method implementation (noncommercial research)

    Metadata checked

  59. 2026ECCVAccepted · proceedings pending

    MOOZY: A Patient-First Foundation Model for Computational Pathology

    Yousef Kotp, Vincent Quoc-Huy Trinh, Christopher Pal, and Mahdi S. Hosseini

    L3

    ECCV 2026 poster presentation is now verified by the official conference program (poster 4955), superseding author-only acceptance evidence. A Springer version of record was not verified on 2026-09-12. The program lists Yousef Hassan whereas the retained arXiv record lists Yousef Kotp; preserve the declared manuscript authorship rather than silently replacing it.

    foundation encoder · MIL / WSI · patient-level representation · case transformer · multi-slide learning · masked self-distillation · self-supervised learning

    Official artifacts: Project · Code · Model · Official ECCV 2026 poster · Conference manuscript

    Metadata checked

  60. 2026MICCAI Efficient Medical AI workshop (EMA)Peer reviewed

    Multi-Teacher Contrastive Distillation for Edge-Efficient Pathology Foundation Models

    Tim Lenz, Maurice Heide, Marco Gustav, Nic G. Reitsam, and Jakob Nikolas Kather

    L3

    Official MICCAI satellite proceedings confirm the 2nd Efficient Medical AI workshop (EMA), not the main MICCAI track. LNCS volume 17265 is listed; DOI and pagination remain pending on the checked record. Full 11-page accepted manuscript inspected. Teachers and students use 2.0 µm/px (5×); this is capacity compression, not a demonstrated 20×→5× transfer method. Raspberry Pi timings concern individual encoder forward passes, not complete WSI processing.

    foundation encoder · self-supervised learning · WSI engineering · knowledge distillation / model transfer · MuCoDi · MuCoEdge · multi-teacher contrastive distillation · edge inference · cached teacher embeddings · same-magnification compression

    Official artifacts: Official workshop accepted manuscript · Author implementation and documented scope

    Metadata checked

  61. pathology VLM · MIL / WSI · few-shot WSI · semantic adaptation · class descriptions

    Official artifacts: Code

    Metadata checked

  62. 2026Findings of EMNLPAccepted · proceedings pending

    MVC-Bench: Benchmarking Calibration of Medical Vision-Language Models

    Ashshak Sharifdeen, Shihab Aaqil Ahamed, Ufaq Khan, Muhammad Akhtar Munir Sujair Ibrahim, Mohamed Rafeek Mareer Ahamed, Yutong Xie, Imran Razzak, and Muhammad Haris Khan

    L3

    The arXiv record reports acceptance to Findings of EMNLP 2026. No final ACL Anthology record was available when checked on 30 August 2026, so claims were verified against arXiv v1 and the official repository.

    pathology VLM · evaluation · robustness / domain shift / privacy · vision–language evaluation / safety · vision evaluation / robustness · evaluation / reproducibility · MVC-Bench · medical VLM calibration · histopathology domain shift · expected calibration error · prompt tuning · multi-class margin regularization

    Official artifacts: Official implementation

    Metadata checked

  63. 2026NeurIPSAccepted · proceedings pending

    Nonparametric Distribution Matching for Self-Supervised Whole-Slide Image Condensation

    Duong M. Nguyen, Trong Nghia Hoang, Hang Thi Nguyen, Thanh Trung Huynh, Phi Le Nguyen, and Minh N. Do

    L3

    Acceptance independently verified by NeurIPS 2026 poster 153235 and author repository. Review uses arXiv:2610.00678v1, submitted 2026-09-30. Repository contained only a README on 2026-10-08. Feature condensation at 20× is not low-magnification encoder distillation; Table 1 tests on full feature bags.

    MIL / WSI · self-supervised learning · WSI engineering · NICER · self-supervised condensation · adaptive prototypes · optimal transport · Poisson point process · feature compression

    Official artifacts: Official NeurIPS 2026 program · Versioned full manuscript · Author repository (README only at audit)

    Metadata checked

  64. pathology VLM · evaluation · text preprocessing · image-observable facts · report hallucination

    Metadata checked

  65. arXiv v1 submitted 10 August 2026; no peer-reviewed venue was verified on 2026-09-02. A single CNN is conditioned on physical pixel size and trained over a continuous magnification range; each prediction still consumes one patch scale and the method is neither MIL nor knowledge distillation.

    WSI engineering · cell / tissue modeling · evaluation · robustness / domain shift / privacy · Conditional Layer Normalization · continuous magnification · pixel-size conditioning · scale robustness · PANDA

    Official artifacts: Official code

    Metadata checked

  66. 2026MIDLPeer reviewed

    PAGET: Hierarchical Multi-Teacher Knowledge Distillation for Comprehensive Tumor Microenvironment Segmentation

    Daisuke Komura, Maki Takao, Mieko Ochi, Takumi Onoyama, Hiroto Katoh, Hiroyuki Abe, Hiroyuki Sano, Teppei Konishi, Toshio Kumasaka, Tomoyuki Yokose, Yohei Miyagi, Tetsuo Ushiku, and Shumpei Ishikawa

    L3

    Peer-reviewed MIDL 2026 proceedings, PMLR 315:256–279; official record verified 2026-10-02.

    cell / tissue modeling · knowledge distillation / model transfer · PAGET · hierarchical multi-teacher distillation · TME segmentation · IHC restaining · semantic segmentation · panoptic segmentation

    Official artifacts: Official proceedings PDF · Official implementation

    Metadata checked

  67. 2026arXivPreprint

    Paired Uterine Whole-Slide Images and Pathology Reports for Multimodal Computational Pathology

    Han Li, Jingsong Liu, Ayako Ura, Junlin Hou, Zhengyang Xu, Azar Kazemi, Oskar Thaeter, Christian Grashei, Fabian Gülhan, Reza Nasirigerdeh, Xun Ma, Rui Yan, Hao Chen, S. Kevin Zhou, Nassir Navab, Carolin Mogler, and Peter Schüffler

    L2–L3

    arXiv preprint submitted 4 July 2026 and revised as v2 on 17 July 2026; no peer-reviewed version was verified on 20 August 2026.

    WSI engineering · pathology VLM · evaluation · TUM-Uteria · uterine pathology · WSI–report pairs · multimodal dataset · report generation · bilingual reports

    Official artifacts: Official gated dataset card

    Metadata checked

  68. 2026arXivPreprint

    PANDA: Prototype-Anchored Alignment for Partially Unpaired Multimodal Learning, with Applications to Alzheimer's MRI and TCGA Pathology

    Sheethal Bhat, Mahfuzur Rahman Chowdhury, Paula Andrea Perez-Toro, Stephan Wunderlich, Rose Dawn Bharat, Siming Bayer, and Andreas Maier

    L3

    arXiv v1 preprint submitted 26 August 2026. The manuscript promises code upon acceptance, but no public implementation was available at the review cutoff.

    spatial / molecular · MIL / WSI · evaluation · PANDA alignment · partially paired modalities · class prototypes · WSI–RNA transfer · survival prediction · primary-modality deployment

    Metadata checked

  69. 2026Pacific Symposium on BiocomputingPeer reviewed

    Patch-level phenotype identification via weakly supervised neuron selection in sparse autoencoders for CLIP-derived pathology embeddings

    Keita Tamura, Yao-zhong Zhang, Yohei Okubo, and Seiya Imoto

    L3

    PSB 2026 volume 31, pages 708–721, with source supplement checked. Neuron discovery uses slide labels, but the reported localization thresholds use patch-level validation annotations. Single-neuron localization does not preserve all multi-feature slide-classification performance.

    MIL / WSI · evaluation · interpretability / attribution · SAE · SAE-1N · BatchTopK · weak supervision · CONCH · phenotype localization

    Official artifacts: Official PSB proceedings PDF · Author implementation and supplement

    Metadata checked

  70. 2026MICCAI MI4MedFM WorkshopAccepted · proceedings pending

    PATH-DISSECT: Interpreting Concept Representation and Classifier Reliance in Pathology Foundation Models with Sparse Autoencoders

    Mayur Parvatikar, Xingjian Li, and Min Xu

    L3

    Official MICCAI 2026 Satellite Events page supplies the 11-page camera-ready; Springer DOI and final pages were pending at inspection. This is MI4MedFM workshop work on tissue patches, not main-conference or patient-level WSI outcome validation. Causal claims concern interventions on a frozen encoder plus linear readout, not biological causation.

    evaluation · robustness / domain shift / privacy · interpretability / attribution · SAE · PATH-DISSECT · TopK sparse autoencoders · concept ablation · linear probe reliance · UNI · Virchow2 · SPIDER

    Official artifacts: Official camera-ready PDF · Author implementation · Workshop OpenReview record

    Metadata checked

  71. Submitted 2026-07-21; retain preprint status and do not treat this benchmark as an established standard.

    pathology VLM · evaluation · agent benchmark · evidence seeking · multiscale navigation

    Metadata checked

  72. pathology VLM · fine-grained alignment · region subcaptions · WSI language

    Official artifacts: Code

    Metadata checked

  73. pathology VLM · agentic diagnosis · evidence seeking · slide highlighter

    Official artifacts: Code

    Metadata checked

  74. pathology VLM · evaluation · reference-free evaluation · grounding · logic and stability

    Official artifacts: Code

    Metadata checked

  75. 2026NeurIPSAccepted · proceedings pending

    PathNavigate: A Training-Free Pathology Agent with Surprise-Guided Scan and Shared Slide Memory for Whole-Slide Image VQA

    Chunze Yang, Qidong Liu, Wenjie Zhao, Yue Tang, Jiusong Ge, Di Zhang, Jiashuai Liu, Lei Wu, Junbo Lu, Ni Zhang, Xian Wu, Zeyu Gao, and Chen Li

    L3

    Official NeurIPS 2026 poster 154224 verifies acceptance; program title shortens 'Whole-Slide Image VQA' to 'Whole-Slide VQA'. Review uses arXiv:2605.23559v1, not an uninspected camera-ready. Backbone-frozen navigation includes test-time memory optimization and high-magnification evidence; not 5×-only deployment.

    pathology VLM · WSI engineering · PathNavigate · WSI VQA · surprise-guided navigation · shared online memory · training-free agents · PLIP

    Official artifacts: Official NeurIPS 2026 program · Versioned full manuscript · Official inference implementation

    Metadata checked

  76. pathology VLM · agentic RAG · retrieval · reinforcement learning

    Official artifacts: Code

    Metadata checked

  77. pathology VLM · reinforcement learning · chain of thought · expert reasoning

    Official artifacts: Code and models

    Metadata checked

  78. 2026MICCAIPeer reviewed

    Pathologist Attention–Aligned Report Generation for Prostate Histopathology

    Ruoyu Xue, Suryakant Singh, Souradeep Chakraborty, Pierre Marza, Oksana Yaskiv, Constantin Friedman, Natallia Sheuka, Paul Friedman, Bharat Ramlal, Beatrice Knudsen, Rajarsi Gupta, Joel Saltz, Prateek Prasanna, Gregory Zelinsky, and Dimitris Samaras

    L3

    Official MICCAI 2026 proceedings record and accepted-version open-access PDF verified 2026-10-02; Springer DOI and pagination remain pending.

    pathology VLM · attention supervision · report generation · prostate pathology

    Official artifacts: Code and attention data · Official MICCAI 2026 proceedings · Official accepted-version PDF

    Metadata checked

  79. pathology VLM · Pathology-CoT · visual chain of thought · expert behavior

    Metadata checked

  80. 2026arXivPreprint

    PathPilot: An Adaptive Question-Conditioned Multi-Magnification Navigation Agent for Whole-Slide Image Analysis

    Zhengyang Xu, Han Li, Jingsong Liu, Ayako Ura, Shihui Zu, Shaohua Kevin Zhou, Nassir Navab, and Peter Schüffler

    L3

    arXiv:2610.16734v1, submitted 12 October 2026; manuscript says under review, with no independently verified acceptance. Full 24-page public manuscript inspected; referenced supplementary material was not attached or independently obtained. Code is promised on publication, not a verified release. Adaptive thumbnail/1.25×/2.5×/5×/10× exploration is not knowledge distillation or low-resolution-only inference. QA scores use a language-model judge; deterministic repeated runs do not establish population uncertainty.

    pathology VLM · WSI engineering · MIL / WSI · PathPilot · CrossMagLoc · EviRegionSearch · multi-magnification navigation · question-conditioned evidence acquisition · WSI question answering

    Official artifacts: Inspected arXiv v1 manuscript

    Metadata checked

  81. Submitted 2026-07-20; retain preprint status pending independent use and a version of record.

    pathology VLM · evaluation · report evaluation · benchmark · clinical factuality

    Metadata checked

  82. 2026ECCVAccepted · proceedings pending

    Pathryoshka: Compressing Pathology Foundation Models via Multi-Teacher Knowledge Distillation With Nested Embeddings

    Christian Grashei, Christian Brechenmacher, Rao Muhammad Umer, Jingsong Liu, Carsten Marr, Peter J. Schüffler, and Ewa Szczurek

    L3

    ECCV 2026 poster status reverified against the official complete program (poster 4454). No oral or spotlight designation is recorded. A Springer version of record was not verified on 2026-09-12; the existing review retains its declared manuscript revision.

    knowledge distillation / model transfer · foundation encoder · evaluation · Pathryoshka · multi-teacher distillation · nested embeddings · foundation-model compression · compact pathology encoder

    Official artifacts: Official ECCV record · Official model · Conference manuscript

    Metadata checked

  83. 2026NeurIPSAccepted · proceedings pending

    PathView-Bench: Can Multimodal Large Language Models Achieve Fine-grained Multiscale Understanding of Pathology Images?

    Zongyi Chen, Yu Liang, Jie Lin, and Liansheng Wang

    L3

    Acceptance independently verified 2026-10-08: official NeurIPS poster 139172 exactly matches the title and four authors and links OpenReview gZJHNK7GHw. The scientific review remains tied to arXiv:2607.28318v1 and its 2026-08-08 full-text audit; this metadata refresh did not re-audit code or dataset availability.

    pathology VLM · evaluation · PathView-Bench · multiscale pathology · MLLM benchmark · vision-grounded evaluation

    Official artifacts: Official NeurIPS 2026 acceptance record

    Metadata checked

  84. 2026arXivPreprint

    Pathway-Structured Privileged Distillation for Deployable Computational Pathology

    Yongxin Guo, Hao Lu, Onur C. Koyun, Zhengjie Zhu, Muhammet F. Demir, and Metin N. Gurcan

    L3

    arXiv v1 (2026-06-01) checked 2026-10-02; no conference acceptance verified. Paired RNA is training-only, while WSI is used at deployment. Pathway-memory readouts are not independently validated molecular measurements.

    spatial / molecular · MIL / WSI · knowledge distillation / model transfer · MoPE · privileged information · RNA-to-WSI distillation · pathway experts · shared memory · morphology slots

    Official artifacts: Versioned manuscript

    Metadata checked

  85. 2026arXivPreprint

    Pretraining Multiple Instance Learning Networks with Multi-Teacher Distillation from Pathology Slide Foundation Models

    Mingxi Fu, Jiawen Li, Renao Yan, Jiali Hu, Qiehe Sun, Tian Guan, and Yonghong He

    L3

    arXiv v1 (2026-07-16) checked 2026-10-02. Six cohorts cover 15 tasks, not 15 independent datasets. Official code and pretrained aggregator checkpoints are listed; experiments were not rerun. This transfers slide embeddings into MIL initialization, not 20×-to-5× acquisition.

    MIL / WSI · foundation encoder · self-supervised learning · knowledge distillation / model transfer · loss / objective design · multi-teacher distillation · MIL pretraining · ADN · TITAN · CARE · aggregator initialization

    Official artifacts: Versioned manuscript · Official implementation and pretrained MIL weights

    Metadata checked

  86. 2026Medical Image AnalysisAccepted · proceedings pending

    RACR-MIL: Rank-aware contextual reasoning for weakly supervised grading of squamous cell carcinoma using whole slide images

    Anirudh Choudhary, Mosbah Aouad, Krishnakant Saboo, Angelina Hwang, Jacob Kechter, Blake Bordeaux, Puneet Bhullar, David DiCaudo, Steven Nelson, Nneka Comfere, Emma Johnson, Olayemi Sokumbi, Jason Sluzevich, Leah Swanson, Dennis Murphree, Aaron Mangold, and Ravishankar Iyer

    L3

    The complete arXiv v3 manuscript identifies Medical Image Analysis as the journal and the abstract record reports acceptance; a final DOI or journal issue record was not yet available when checked on 30 August 2026.

    MIL / WSI · evaluation · loss / objective design · RACR-MIL · ordinal grading · hybrid WSI graph · rank-aware attention · squamous cell carcinoma · pathologist reader study

    Metadata checked

  87. evaluation · WSI engineering · DPA recommendation · clinical laboratory · AI validation

    Metadata checked

  88. arXiv v1 submitted 31 August 2026. The authors released reproducibility deposits on Zenodo; no peer-reviewed record was verified on 2 September 2026.

    WSI engineering · evaluation · robustness / domain shift / privacy · evaluation / reproducibility · artifact detection · WSI quality control · reproducibility · bootstrap uncertainty · partition sensitivity · preprocessing confounding

    Official artifacts: Official reproducibility deposit · Referenced benchmark artifact deposit

    Metadata checked

  89. 2026MIDLPeer reviewed

    Revisiting foundation models for cell instance segmentation

    Anwai Archit and Constantin Pape

    L2–L3

    cell / tissue modeling · evaluation · instance segmentation · foundation-model comparison · SAM

    Metadata checked

  90. 2026arXivPreprint

    Robustifying pathology foundation models via fine-tuning

    Alexandre Filiot, Oskar Thaeter, Benoit Schmauch, and Lionel Guillou

    L3

    foundation encoder · evaluation · foundation-model fine-tuning · scanner robustness · stain robustness · PathoROB

    Official artifacts: Released models

    Metadata checked

  91. 2026MICCAIPeer reviewed

    SAM-Cluster and SAM-LP: Structure-Aware Evaluation Metrics for Selecting WSI Feature Extractors Without MIL Training

    Juhyeon Kim, Paul Ssemakula, Chanjae Song, and Mun Yong Yi

    L3

    Official MICCAI 2026 open-access proceedings version. Springer DOI and final page range were not listed at the audit date.

    evaluation · foundation encoder · MIL / WSI · WSI engineering · SAM-Cluster · SAM-LP · feature extractor selection · WSI representation evaluation · Spearman correlation · model selection

    Official artifacts: Official accepted-version PDF · Official implementation and benchmark results

    Metadata checked

  92. 2026ECCVAccepted · proceedings pending

    Scaling Whole-Slide Pathology Foundation Model Pretraining with Billions Off-the-Shelf Tokens

    Honglin Li, Zhongyi Shui, Chenglu Zhu, and Lin Yang

    L3

    ECCV 2026 acceptance and the manuscript are verified from the official program. No Springer version of record or author-owned public code/checkpoint was verified. Section 4.1 explicitly combines HistAI with about 10,000 private WSIs; do not describe pretraining as public-only. PathTokScale and PathTokenScaling both occur in the manuscript.

    foundation encoder · self-supervised learning · MIL / WSI · WSI engineering · PathTokScale · TokRet · spatial tokens · token retention · sparse attention · DINOv2 · ECCV 2026 poster

    Official artifacts: Official ECCV 2026 Poster

    Metadata checked

  93. 2026Nature CommunicationsPeer reviewed

    sCellST predicts single-cell gene expression from H&E images

    Loïc Chadoutaud et al.

    L3

    spatial / molecular · cell / tissue modeling · single-cell expression · weak supervision · nuclei detection

    Metadata checked

  94. spatial / molecular · MIL / WSI · evaluation · triple-negative breast cancer · recurrence-risk heatmaps · spatial proteomics · AI-guided sampling

    Metadata checked

  95. self-supervised learning · foundation encoder · StainNet · IHC · special stains

    Metadata checked

  96. 2026Medical Image AnalysisPeer reviewed

    Streamline Pathology Foundation Model by Cross-Magnification Distillation

    Ziyu Su, Abdul Rehman Akbar, Usama Sajjad, Anil V. Parwani, and Muhammad Khalid Khan Niazi

    L3

    Journal record verified through publisher metadata, Crossref and PubMed PMID 42874158 on 26 October 2026: electronic publication 10 October 2026, assigned to volume 115 (January 2027), article 104352. The stable ID retains the 2025 preprint year. Journal full text was unavailable; detailed scientific claims and visuals remain explicitly tied to the previously inspected arXiv v3, not asserted to match the journal version. The journal abstract describes seven tasks and encoder-level throughput, not an end-to-end speedup.

    knowledge distillation / model transfer · foundation encoder · self-supervised learning · WSI engineering · evaluation · XMAG · cross-magnification distillation · UNI2 teacher · compact pathology encoder · 5× inference

    Official artifacts: Inspected author manuscript (v3) · PubMed journal metadata and abstract · Official code · Official model

    Metadata checked

  97. 2026ECCVAccepted · proceedings pending

    SurvMILKD: A Weakly Supervised Survival Analysis Framework for Multi-Teacher Knowledge Distillation using Pathology Foundation Models

    Mayur Mallya, Ali Khajegili Mirabadi, Hossein Farahani, and Ali Bashashati

    L3

    The official ECCV 2026 poster and conference-hosted manuscript verify acceptance; a Springer version of record was not verified. The official repository was a code-coming-soon placeholder on 2026-09-12. All foundation encoders remain frozen: task-specific MIL adapters and translation modules learn, not the UNI backbone.

    MIL / WSI · foundation encoder · evaluation · knowledge distillation / model transfer · SurvMILKD · survival analysis · multi-teacher distillation · risk-aware distillation · frozen encoders · ABMIL · ECCV 2026 poster

    Official artifacts: Official ECCV 2026 Poster · Official repository — code pending

    Metadata checked

  98. 2026ECCVAccepted · proceedings pending

    TaxoMIL: Taxonomy-Constrained Learning for Hierarchical Whole Slide Image Analysis

    Chaeyeon Lee, Khang Nguyen Quoc, Jinsol Song, Yosep Chong, Kwangil Yim, and Jin Tae Kwak

    L3

    Official ECCV 2026 poster and conference-hosted manuscript verify acceptance; no Springer version of record was verified. Author spelling follows the paper rather than the abbreviated program entry. Output is coarse/fine diagnostic label text, not full clinical reports. GastWSI is private.

    MIL / WSI · pathology VLM · evaluation · TaxoMIL · hierarchical diagnosis · label-text generation · taxonomy · GPT-2 · ECCV 2026 poster

    Official artifacts: Official ECCV 2026 Poster · Official implementation · arXiv manuscript

    Metadata checked

  99. 2026CVPRPeer reviewed

    TopoSlide: Topologically-Informed Histopathology Whole Slide Image Representation Learning

    Shahira Abousamra, Asmita Sood, and Sylvia Plevritis

    L2–L3

    foundation encoder · MIL / WSI · slide representation · topology · persistent homology · self-supervised learning

    Official artifacts: Code and models

    Metadata checked

  100. 2026Nature CommunicationsPeer reviewed

    Towards Robust Foundation Models for Digital Pathology

    Jonah Kömen et al.

    L3

    foundation encoder · PathoROB · robustness · site signature · robustness / domain shift / privacy

    Metadata checked

  101. 2026ICLRPeer reviewed

    TRACE: Your Diffusion Model Is Secretly an Instance Edge Detector

    Sanghyun Jo, Ziseok Lee, Wooyeol Lee, Jonghyun Choi, Jaesik Park, Kyungsu Kim

    L3

    Official ICLR 2026 oral and full proceedings manuscript checked. Diffusion-boundary self-distillation improves selected natural-image segmentation but degrades MoNuSeg/TNBC cell segmentation. One-pass speed is edge extraction only, with the large backbone retained. No WSI or cross-magnification validation; official code/checkpoints remain promised rather than released at the checked revision.

    knowledge distillation / model transfer · detection / segmentation · visual representation learning · TRACE · ICLR 2026 oral · self-distillation · diffusion attention · instance edges · negative transfer · histology domain shift · cell / tissue modeling

    Official artifacts: OpenReview · Official project · Official repository — release pending

    Metadata checked

  102. The arXiv record describes the manuscript as under review; this catalog retains preprint status.

    evaluation · pathology VLM · ZIO · out-of-distribution detection · training-free · pathology vision-language model · robustness / domain shift / privacy

    Official artifacts: Official code

    Metadata checked

  103. 2026CVPRPeer reviewed

    Turning Pre-Trained Vision Transformers into End-to-End Histopathology Whole Slide Image Models for Survival Prediction

    Jiawen Li, Jiali Hu, Xitong Ling, Renao Yan, Yuxuan Chen, Tian Guan, and Yonghong He

    L3

    MIL / WSI · spatial / molecular · end-to-end WSI · survival · vision transformer

    Metadata checked

  104. 2026arXivPreprint

    Understanding Synergistic Interactions among Pathology Foundation Models via Adaptive Fusion

    Yuxiang Xiao, Yang Hu, Bin Li, Tianyang Zhang, Zexi Li, Huazhu Fu, Jens Rittscher, and Kaixiang Yang

    L3

    foundation encoder · MIL / WSI · evaluation · PathoOracle · adaptive encoder fusion · foundation model complementarity · mixture of experts

    Official artifacts: Official code

    Metadata checked

  105. MIL / WSI · few-shot WSI · dynamic knowledge · MIL

    Metadata checked

  106. 2026NeurIPSAccepted · proceedings pending

    VIPER: An Expert-Curated Benchmark for Vision-Language Models in Veterinary Pathology

    Luca L. Weishaupt, Simone de Brot, Javier Asin, Llorenç Grau-Roma, Nic G. Reitsam, Andrew H. Song, Dongmin Bang, Stefan T. Kaluziak, Long Phi Le, Jakob Nikolas Kather, Faisal Mahmood, and Guillaume Jaume

    L3

    Acceptance independently verified 2026-10-08 through official NeurIPS poster 139742: exact title and matching 12-author list, linked OpenReview 7986DZ9rPe. Scientific review and artifact checks remain tied to arXiv:2608.26382v1 and the 2026-08-30 audit, not a refreshed full-text/code/data inspection. VIPER evaluates rat toxicologic regions rather than whole-slide images; it is an ROI benchmark, not a WSI benchmark.

    pathology VLM · evaluation · robustness / domain shift / privacy · vision–language evaluation / safety · VIPER · veterinary pathology · toxicologic pathology · expert-curated VQA · visual grounding audit · domain transfer

    Official artifacts: Official evaluation code and documentation · Official benchmark dataset · Official NeurIPS 2026 acceptance record

    Metadata checked

  107. foundation encoder · evaluation · patient-level benchmark · foundation-model atlas · signal attribution · leakage control

    Official artifacts: OpenTME data

    Metadata checked

  108. Public arXiv v2 (2026-10-01) verified 2026-10-02. The authors state ICLR 2027 under review; no acceptance inferred. Only public source material was used. A diagnostic study of target utility, predictability and downstream benefit, not a new universally superior distillation architecture.

    MIL / WSI · evaluation · foundation encoder · knowledge distillation / model transfer · evaluation / reproducibility · cross-magnification distillation · 5× to 20× · residual prediction · teacher target utility · conditional mean · WSI evaluation

    Official artifacts: Reviewed manuscript revision

    Metadata checked

  109. 2026arXivPreprint

    Whole-Slide Image Analysis under Realistic Few-Shot Annotation Protocols

    Tiffanie Godelaine, Maxime Zanella, Karim El Khoury, Benoit Macq, and Christophe De Vleeschouwer

    L3

    arXiv v1 submitted 31 August 2026; the manuscript title page says it was submitted on 29 July 2026. Code and data instructions were released, but no peer-reviewed record was verified on 2 September 2026.

    cell / tissue modeling · pathology VLM · evaluation · SlideCRF · few-shot transduction · WSI patch classification · pathologist clicks · scribble annotation · absent classes

    Official artifacts: Official implementation and data instructions

    Metadata checked

  110. 2026arXivPreprint

    WILSON - a pathology foundation model framework for patient-level analysis and diagnostic text generation

    Saghir Alfasly, Wataru Uegami, Sobhan Hemati, Wenchao Han, Xiaojia Tang, Kevin Thompson, Daniel Stone, Ghazal Alabtah, Saba Yasir, Michael R. Lucas, Eric W. Klee, Cheryl L. Willman, Judy C. Boughey, Matthew P. Goetz, Krishna R. Kalari, and H. R. Tizhoosh

    L3

    arXiv v1 submitted 2026-09-20. No peer-reviewed record was verified. The manuscript says model release is planned after publication and institutional clearance; Mayo training WSIs/reports are not publicly downloadable.

    foundation encoder · pathology VLM · MIL / WSI · self-supervised learning · WSI engineering · WILSON · multi-magnification composites · patient-level foundation model · report embedding distillation · CoCa · case-level retrieval

    Official artifacts: Full manuscript and supplementary material

    Metadata checked

  111. 2025CVPRPeer reviewed

    2DMamba: Efficient State Space Model for Image Representation with Applications on Giga-Pixel Whole Slide Image Classification

    Jingwei Zhang, Anh Tien Nguyen, Xi Han, Vincent Quoc-Huy Trinh, Hong Qin, Dimitris Samaras, and Mahdi S. Hosseini

    L3

    MIL / WSI · 2D state-space model · spatial ordering · WSI classification

    Official artifacts: Code

    Metadata checked

  112. 2025Nature CommunicationsPeer reviewed

    A clinical benchmark of public self-supervised pathology foundation models

    Campanella et al.

    L3

    self-supervised learning · foundation encoder · evaluation · clinical benchmark · contamination audit · compute

    Metadata checked

  113. self-supervised learning · foundation encoder · GPFM · knowledge distillation · hybrid supervision · knowledge distillation / model transfer

    Metadata checked

  114. 2025Nature CommunicationsPeer reviewed

    A Multimodal Knowledge-Enhanced Whole-Slide Pathology Foundation Model

    Yingxue Xu et al.

    L3

    foundation encoder · pathology VLM · mSTAR · slide–report alignment · spatial transcriptomics

    Metadata checked

  115. 2025Nature MedicinePeer reviewed

    A Multimodal Whole-Slide Foundation Model for Pathology

    Ding et al.

    L3

    foundation encoder · pathology VLM · TITAN · multimodal WSI · slide representation

    Metadata checked

  116. 2025NaturePeer reviewed

    A Vision–Language Foundation Model for Precision Oncology

    Jinxi Xiang et al.

    L3

    foundation encoder · MUSK · vision–language encoder · precision oncology · pathology VLM

    Metadata checked

  117. spatial / molecular · foundation encoder · OmiCLIP · Loki · visual-omics foundation model

    Metadata checked

  118. pathology VLM · cell / tissue modeling · zero-shot segmentation · active learning · language grounding

    Metadata checked

  119. 2025MICCAIPeer reviewed

    AEM: Attention Entropy Maximization for Multiple Instance Learning based Whole Slide Image Classification

    Yunlong Zhang, Honglin Li, Yuxuan Sun, Zhongyi Shui, Jingxiong Li, Chenglu Zhu, and Lin Yang

    L3

    loss / objective design · MIL / WSI · attention entropy maximization · multiple instance learning · whole-slide classification · cosine weight annealing · attention regularization

    Official artifacts: Official code

    Metadata checked

  120. self-supervised learning · foundation encoder · evaluation · STAMP benchmark · feature extraction · external validation

    Metadata checked

  121. 2025Nature MethodsPeer reviewed

    CellSAM: a foundation model for cell segmentation

    Markus Marks et al.

    L2

    cell / tissue modeling · cell segmentation · foundation model · general microscopy

    Metadata checked

  122. 2025WACVPeer reviewed

    CEMIL: Contextual Attention Based Efficient Weakly Supervised Approach for Histopathology Image Classification

    Tawsifur Rahman, Alexander S. Baras, and Rama Chellappa

    L3

    Peer-reviewed WACV 2025 proceedings paper, pages 4248–4257.

    knowledge distillation / model transfer · MIL / WSI · WSI engineering · CEMIL · patch selection · instructor–learner distillation · contextual attention · efficient MIL

    Metadata checked

  123. MIL / WSI · continual MIL · localization · catastrophic forgetting

    Metadata checked

  124. pathology VLM · patch and WSI · VQA · visual referring

    Official artifacts: Code

    Metadata checked

  125. pathology VLM · CPathAgent · active navigation · multiscale agent

    Metadata checked

  126. MIL / WSI · instance ordering · jigsaw · MIL alternative

    Metadata checked

  127. 2025MICCAIPeer reviewed

    Distilling Foundation Models for Robust and Efficient Models in Digital Pathology

    Alexandre Filiot, Nicolas Dop, Oussama Tchita, Auriane Riou, Rémy Dubois, Thomas Peeters, Daria Valter, Marin Scalbert, Charlie Saillard, Geneviève Robin, and Antoine Olivier

    L3

    Peer-reviewed MICCAI 2025 proceedings paper.

    knowledge distillation / model transfer · foundation encoder · evaluation · robustness / domain shift / privacy · H0-mini · foundation-model distillation · compact encoder · scanner robustness · stain robustness

    Official artifacts: Official model · Official robustness benchmark

    Metadata checked

  128. 2025ICMLPeer reviewed

    Do Multiple Instance Learning Models Transfer?

    Daniel Shao et al.

    L3

    MIL / WSI · FEATHER · MIL transfer · pan-cancer pretraining

    Metadata checked

  129. First submitted in 2025 and revised in 2026; no version of record was located by 2026-07-27.

    pathology VLM · PathChat+ · SlideSeek · multi-agent WSI search

    Metadata checked

  130. foundation encoder · MIL / WSI · EXAONE Path · slide-label supervision · patch representation

    Metadata checked

  131. 2025arXivPreprint

    EXAONE Path 2.5: Pathology Foundation Model with Multi-Omics Alignment

    Juseung Yun, Sunwoo Yu, Sumin Ha, Jonghyun Kim, Janghyeon Lee, Jongseong Jang, and Soonyoung Lee

    L3

    foundation encoder · pathology VLM · spatial / molecular · EXAONE Path · multi-omics alignment · SigLIP

    Official artifacts: Model

    Metadata checked

  132. 2025WACVPeer reviewed

    F2FLDM: Latent Diffusion Models with Histopathology Pre-Trained Embeddings for Unpaired Frozen Section to FFPE Translation

    Man M. Ho, Shikha Dubey, Yosep Chong, Beatrice Knudsen, and Tolga Tasdizen

    L3

    generative / virtual pathology · robustness / domain shift / privacy · evaluation · frozen section · FFPE translation · unpaired diffusion · pathology embeddings

    Official artifacts: Author preprint · Official project page

    Metadata checked

  133. MIL / WSI · hierarchical distillation · multi-resolution · efficiency · knowledge distillation / model transfer

    Official artifacts: Code

    Metadata checked

  134. MIL / WSI · pathology VLM · few-shot WSI · language guidance · token compression

    Metadata checked

  135. evaluation · FUTURE-AI · trustworthy AI · deployment

    Metadata checked

  136. self-supervised learning · foundation encoder · vision-concept contrast · gigapixel pretraining · slide representation

    Official artifacts: Code

    Metadata checked

  137. 2025Nature CommunicationsPeer reviewed

    Generating Dermatopathology Reports from Gigapixel Whole Slide Images with HistoGPT

    Manuel Tran et al.

    L3

    pathology VLM · HistoGPT · report generation · dermatopathology

    Metadata checked

  138. 2025IMDRFGuideline

    Good machine learning practice for medical device development: Guiding principles

    International Medical Device Regulators Forum

    L3

    IMDRF/AIML WG/N88 FINAL:2025, finalized 2025-01-29.

    evaluation · GMLP · medical device · lifecycle

    Metadata checked

  139. pathology VLM · evaluation · report evaluation · entities and relations · clinical errors

    Official artifacts: Code

    Metadata checked

  140. L3

    Peer-reviewed CVPR 2025 proceedings paper, pages 30251–30260.

    MIL / WSI · HistoFS · federated style transfer · non-IID WSI classification · feature-space AdaIN · ROI-preserving attention · robustness / domain shift / privacy

    Official artifacts: Official project · Official code

    Metadata checked

  141. spatial / molecular · evaluation · Angioscore · IMmotion150 · treatment response

    Metadata checked

  142. pathology VLM · historical reports · bi-modal learning · report generation

    Official artifacts: Code

    Metadata checked

  143. 2025Scientific ReportsPeer reviewed

    Human Visual Attention-Inspired Knowledge Distillation Underlying Interpretable Computational Pathology

    Muzhou Yu, Zihan Zhong, Xingang Zhou, Yuekun Wang, Tingyu Liang, Jiamin Chen, Hongmin Huang, Junhan Zhou, Dachun Zhao, Bo Lei, Yu Wang, Wenbin Ma, and Kaisheng Ma

    L3

    Peer-reviewed open-access journal article 15:42124. Low- and high-magnification language motivates the design, but HVisKD transfers sample- and region-relation features between teacher and student given the same pathology patches; it is not cross-magnification distillation.

    knowledge distillation / model transfer · interpretability / attribution · cell / tissue modeling · WSI engineering · evaluation · HVisKD · relation distillation · interpretable distillation · GBM tissue mapping · lightweight CNN

    Official artifacts: Open-access article · Official code

    Metadata checked

  144. MIL / WSI · PAMoE · tissue heterogeneity · mixture of experts

    Metadata checked

  145. 2025arXivPreprint

    Magnification-Aware Distillation (MAD): A Self-Supervised Framework for Unified Representation Learning in Gigapixel Whole-Slide Images

    Mahmut S. Gokmen, Mitchell A. Klusty, Peter T. Nelson, Allison M. Neltner, Sen-Ching Samson Cheung, Thomas M. Pearce, David A. Gutman, Brittany N. Dugger, Devavrat S. Bisht, Margaret E. Flanagan, and V. K. Cody Bumgardner

    L3

    Preprint; arXiv comments report submission to the AMIA 2026 Informatics Summit, not acceptance.

    knowledge distillation / model transfer · foundation encoder · self-supervised learning · WSI engineering · MAD · magnification-aware distillation · resolution-invariant embeddings · neuropathology

    Official artifacts: Official model

    Metadata checked

  146. Final U.S. FDA guidance issued August 2025; jurisdiction-specific.

    evaluation · PCCP · change management · medical device

    Metadata checked

  147. MIL / WSI · foundation encoder · spatial / molecular · multimodal adapters · slide foundation model · multi-task adaptation

    Metadata checked

  148. spatial / molecular · THREADS · molecular pretraining · slide foundation model · foundation encoder

    Metadata checked

  149. 2025MICCAIPeer reviewed

    Multi-modal Knowledge Decomposition based Online Distillation for Biomarker Prediction in Breast Cancer Histopathology

    Qibin Zhang, Xinyu Hao, Qiao Chen, Rui Xu, Fengyu Cong, Cheng Lu, and Hongming Xu

    L3

    knowledge distillation / model transfer · spatial / molecular · MIL / WSI · whole-slide image · genomics · biomarker prediction · online distillation · knowledge decomposition

    Official artifacts: Official code

    Metadata checked

  150. pathology VLM · multi-resolution · text-guided visual learning · TCGA

    Official artifacts: Code

    Metadata checked

  151. 2025ICCVPeer reviewed

    PathDiff: Histopathology Image Synthesis with Unpaired Text and Mask Conditions

    Mahesh Bhosale, Abdul Wasi, Yuanhao Zhai, Yunjie Tian, Samuel Border, Nan Xi, Pinaki Sarder, Junsong Yuan, David Doermann, and Xuan Gong

    L3

    generative / virtual pathology · cell / tissue modeling · pathology VLM · histopathology synthesis · unpaired conditioning · text-to-image · mask-to-image

    Official artifacts: Official code

    Metadata checked

  152. pathology VLM · multi-agent · WSI navigation · diagnostic decision support

    Official artifacts: Project, code, and data

    Metadata checked

  153. pathology VLM · synthetic captions · image-text dataset · multi-agent generation

    Official artifacts: Data, code, and models

    Metadata checked

  154. 2025IEEE AccessPeer reviewed

    PatHME: Hierarchical Multi-Expert Knowledge Distillation for Whole Slide Image Analysis

    Jing Wei Tan, Gangsu Kim, and Won-Ki Jeong

    L3

    Peer-reviewed journal article 13:163246–163257.

    knowledge distillation / model transfer · MIL / WSI · foundation encoder · WSI engineering · PatHME · multi-expert distillation · prompt-guided multiscale transfer · hierarchical attention · pathology foundation models

    Official artifacts: Official code

    Metadata checked

  155. 2025MICCAIPeer reviewed

    PathoCellBench: A Comprehensive Benchmark for Cell Phenotyping

    Jérôme Lüscher et al.

    L2–L3

    cell / tissue modeling · evaluation · cell phenotyping · benchmark · multiplex-derived labels

    Metadata checked

  156. 2025Findings of EMNLPPeer reviewed

    PathoHR: Hierarchical Reasoning for Vision-Language Models in Pathology

    Yating Huang et al.

    L3

    pathology VLM · evaluation · hierarchical reasoning · compositional semantics · benchmark

    Metadata checked

  157. pathology VLM · report generation · multimodal representation · melanocytic lesions

    Metadata checked

  158. self-supervised learning · foundation encoder · PathOrchestra · DINOv2 · task breadth

    Metadata checked

  159. L3

    pathology VLM · evaluation · visual grounding · referring expressions · localization benchmark

    Official artifacts: Code and data

    Metadata checked

  160. WSI engineering · evaluation · scanner calibration · color · domain shift · robustness / domain shift / privacy

    Metadata checked

  161. pathology VLM · multi-slide reports · case-level generation · long context

    Metadata checked

  162. foundation encoder · PRISM2 · slide encoder · clinical dialogue · pathology VLM

    Metadata checked

  163. evaluation · PROBAST+AI · risk of bias · applicability

    Metadata checked

  164. 2025MICCAIPeer reviewed

    Prototype-Based Multiple Instance Learning for Gigapixel Whole Slide Image Classification

    Susu Sun, Dominique van Midden, Geert Litjens, and Christian F. Baumgartner

    L3

    Official MICCAI 2025 record and 11-page accepted manuscript checked. PANDA is evaluated as binary tumor classification in this study, not the original six-class ISUP grading task. Artifact concepts are masked before MIL retraining; this is not a universal AUC improvement.

    MIL / WSI · evaluation · interpretability / attribution · SAE · ProtoMIL · sparse autoencoders · concept intervention · additive MIL · CONCH

    Official artifacts: Official MICCAI open-access record · Official accepted manuscript · Author implementation · arXiv manuscript

    Metadata checked

  165. 2025ICMLPeer reviewed

    Scalable Generation of Spatial Transcriptomics from Histology Images via Whole-Slide Flow Matching

    Tinglin Huang, Tianyu Liu, Mehrtash Babadi, Wengong Jin, and Rex Ying

    L3

    spatial / molecular · generative / virtual pathology · STFlow · whole-slide flow matching · spatial transcriptomics · local spatial attention · generative / representation learning · generative vision

    Official artifacts: Official code

    Metadata checked

  166. 2025MIDLPeer reviewed

    Segment Anything for Histopathology

    Griebel et al.

    L3

    cell / tissue modeling · PathoSAM · interactive segmentation · foundation model

    Metadata checked

  167. 2025Nature MethodsPeer reviewed

    Segment Anything for Microscopy

    Anwai Archit et al.

    L2

    Published online in 2024 and assigned to the 2025 volume.

    cell / tissue modeling · μSAM · microscopy segmentation · interactive segmentation

    Metadata checked

  168. cell / tissue modeling · self-supervised learning · evaluation · histomorphology · AVANT trial material · retrospective transfer

    Metadata checked

  169. 2025NeurIPSPeer reviewed

    Semantic and Visual Crop-Guided Diffusion Models for Heterogeneous Tissue Synthesis in Histopathology

    Saghir Alfasly, Wataru Uegami, Md Enamul Hoq, Ghazal Alabtah, and Hamid Tizhoosh

    L3

    generative / virtual pathology · cell / tissue modeling · evaluation · visual crop conditioning · semantic maps · heterogeneous tissue · synthetic segmentation data

    Official artifacts: Author preprint

    Metadata checked

  170. pathology VLM · whole-slide assistant · slide instruction · VQA

    Official artifacts: Code, model, and data

    Metadata checked

  171. spatial / molecular · STPath · spatial transcriptomics · generative model

    Metadata checked

  172. L3

    cell / tissue modeling · spatial / molecular · HistoCell · cell spatial profiles · super-resolution inference

    Metadata checked

  173. evaluation · STARD-AI · diagnostic accuracy · reporting guideline

    Metadata checked

  174. L3

    pathology VLM · evaluation · TRIPOD-LLM · reporting guideline · large language models

    Metadata checked

  175. 2025CVPRPeer reviewed

    TopoCellGen: Generating Histopathology Cell Topology with a Diffusion Model

    Meilong Xu, Saumya Gupta, Xiaoling Hu, Chen Li, Shahira Abousamra, Dimitris Samaras, Prateek Prasanna, and Chao Chen

    L3

    generative / virtual pathology · cell / tissue modeling · evaluation · cell topology generation · topological diffusion · TopoFD · tissue microenvironment

    Official artifacts: Official code

    Metadata checked

  176. 2025MICCAIPeer reviewed

    Unsupervised Anomaly Detection on Preclinical Liver H&E Whole Slide Images Using Graph-Based Feature Distillation

    Lin Li, Lillie Shelton, Thomas Forest, Kyathanahalli Janardhan, Tiffany Jenkins, Michael J. Napolitano, Roujia Wang, David Leigh, Tosha Shah, Grady Earl Carlson, Rajath Soans, and Antong Chen

    L3

    Peer-reviewed MICCAI 2025 proceedings paper; evaluated on preclinical rat-liver H&E WSIs. The author project page requests email contact for code access and showed code as coming soon when checked on 2026-08-23.

    knowledge distillation / model transfer · WSI engineering · evaluation · GraphTox · graph feature distillation · unsupervised anomaly detection · preclinical toxicology · resolution-aware encoder

    Official artifacts: Author project and code-access page

    Metadata checked

  177. 2025CVPRPeer reviewed

    Unsupervised Foundation Model-Agnostic Slide-Level Representation Learning

    Tim Lenz, Peter Neidlinger, Marta Ligero, Georg Wölflein, Marko van Treeck, and Jakob N. Kather

    L3

    self-supervised learning · foundation encoder · MIL / WSI · COBRA · foundation-model agnostic · slide SSL

    Official artifacts: Code

    Metadata checked

  178. L2–L3

    self-supervised learning · foundation encoder · Virchow · DINOv2 · tile encoder

    Metadata checked

  179. 2024IEEE Transactions on Medical ImagingPeer reviewed

    A Graph-Based Multi-Scale Approach With Knowledge Distillation for WSI Classification

    Gianpaolo Bontempo, Federico Bolelli, Angelo Porrello, Simone Calderara, and Elisa Ficarra

    L3

    Peer-reviewed journal article 43(4):1412–1421; journal extension of DAS-MIL.

    knowledge distillation / model transfer · MIL / WSI · WSI engineering · DAS-MIL · multiscale graph · self-distillation · spatial correlation · whole-slide classification

    Official artifacts: Official code

    Metadata checked

  180. 2024NaturePeer reviewed

    A Multimodal Generative AI Copilot for Human Pathology

    Ming Y. Lu et al.

    L3

    pathology VLM · PathChat · multimodal assistant · instruction tuning

    Metadata checked

  181. foundation encoder · CHIEF · slide encoder · weak supervision

    Metadata checked

  182. 2024Nature MedicinePeer reviewed

    A Visual-Language Foundation Model for Computational Pathology

    Ming Y. Lu et al.

    L2–L3

    foundation encoder · pathology VLM · CONCH · image–text alignment · zero-shot

    Metadata checked

  183. self-supervised learning · foundation encoder · Prov-GigaPath · tile encoder · slide encoder

    Metadata checked

  184. 2024Medical Image AnalysisPeer reviewed

    CellViT: Vision Transformers for Precise Cell Segmentation and Classification

    Hörst et al.

    L3

    cell / tissue modeling · CellViT · vision transformer · nuclei

    Metadata checked

  185. 2024Radiology: Artificial IntelligenceGuideline

    Checklist for Artificial Intelligence in Medical Imaging: 2024 Update

    Tejani et al.

    L2

    evaluation · CLAIM · reporting guideline · medical imaging

    Metadata checked

  186. cell / tissue modeling · CoNIC · nuclei · counting

    Metadata checked

  187. pathology VLM · zero-shot learning · many-to-many alignment · pathology dictionary

    Official artifacts: Project

    Metadata checked

  188. 2024WACVPeer reviewed

    Diffusion-Based Generation of Histopathological Whole Slide Images at a Gigapixel Scale

    Robert Harb, Thomas Pock, and Heimo Müller

    L2–L3

    generative / virtual pathology · WSI engineering · evaluation · gigapixel WSI synthesis · coarse-to-fine diffusion · synthetic histopathology · pathologist study

    Official artifacts: arXiv

    Metadata checked

  189. 2024TMLRPeer reviewed

    DINOv2: Learning Robust Visual Features without Supervision

    Maxime Oquab et al.

    Research

    self-supervised learning · DINOv2 · scaling · visual representation learning

    Metadata checked

  190. 2024arXivPreprint

    EXAONEPath 1.0 Patch-level Foundation Model for Pathology

    Juseung Yun, Yi Hu, Jinhyung Kim, Jongseong Jang, and Soonyoung Lee

    L2–L3

    self-supervised learning · foundation encoder · EXAONE Path · stain normalization · patch SSL

    Official artifacts: Code and model

    Metadata checked

  191. MIL / WSI · RRT-MIL · feature re-embedding · local–global context

    Metadata checked

  192. L2–L3

    WSI engineering · quality control · artifact segmentation · multi-site

    Metadata checked

  193. 2024NeurIPS Datasets and BenchmarksPeer reviewed

    HEST-1k: A Dataset for Spatial Transcriptomics and Histology Image Analysis

    Jaume et al.

    L2–L3

    spatial / molecular · HEST-1k · spatial transcriptomics · benchmark

    Metadata checked

  194. pathology VLM · report generation · local-global encoding · cross-modal context

    Official artifacts: Code

    Metadata checked

  195. spatial / molecular · iStar · super-resolution · spatial transcriptomics

    Metadata checked

  196. 2024arXivPreprint

    Learning biologically relevant features in a pathology foundation model using sparse autoencoders

    Nhat Minh Le, Ciyue Shen, Neel Patel, Chintan Shah, Darpan Sanghavi, Blake Martin, Alfred Eng, Daniel Shenker, Harshith Padigela, Raymond Biju, Syed Ashar Javed, Jennifer Hipp, John Abel, Harsha Pokkalla, Sean Grullon, and Dinkar Juyal

    L3

    Review uses arXiv:2407.10785v3, including its supplement. A later NeurIPS 2025 Imageomics workshop paper has the title Evaluating the Utility of Sparse Autoencoders for Interpreting a Pathology Foundation Model; its inaccessible full PDF was not used to replace this version's claims or publication status.

    evaluation · interpretability / attribution · SAE · sparse autoencoders · PLUTO · cell-count correlations · layer-wise representations · mechanistic interpretability

    Official artifacts: Versioned full manuscript · Authors' later Imageomics workshop publication

    Metadata checked

  197. MIL / WSI · MambaMIL · state-space model · sequence reordering

    Metadata checked

  198. spatial / molecular · SurvPath · biological pathways · multimodal survival

    Metadata checked

  199. self-supervised learning · PANTHER · morphological prototypes · slide representation · MIL / WSI · foundation encoder

    Metadata checked

  200. spatial / molecular · multimodal prototypes · survival · efficient fusion

    Metadata checked

  201. self-supervised learning · MADELEINE · multistain · slide representation · MIL / WSI · foundation encoder

    Metadata checked

  202. 2024MICCAI COMPAY workshopPeer reviewed

    PathAlign: A Vision-Language Model for Whole Slide Images in Histopathology

    Faruk Ahmed et al.

    L2–L3

    pathology VLM · WSI-report alignment · weak pairing · workshop paper

    Metadata checked

  203. pathology VLM · assistant · instruction tuning · tool use

    Official artifacts: Code

    Metadata checked

  204. 2024WACVPeer reviewed

    PathLDM: Text Conditioned Latent Diffusion Model for Histopathology

    Srikar Yellapragada, Alexandros Graikos, Prateek Prasanna, Tahsin Kurc, Joel Saltz, and Dimitris Samaras

    L3

    generative / virtual pathology · pathology VLM · text-conditioned latent diffusion · pathology reports · cyclic positional encoding · TCGA-BRCA

    Official artifacts: Author preprint · Official code

    Metadata checked

  205. pathology VLM · PathMMU · multimodal benchmark · visual reasoning

    Metadata checked

  206. self-supervised learning · PathoDuet · cross-stain · multiscale

    Metadata checked

  207. self-supervised learning · foundation encoder · Phikon-v2 · DINOv2 · biomarker prediction

    Metadata checked

  208. foundation encoder · PRISM · slide encoder · report alignment · pathology VLM

    Metadata checked

  209. pathology VLM · visual instruction tuning · localized narratives · video provenance

    Official artifacts: Project

    Metadata checked

  210. 2024ISBIPeer reviewed

    Reducing Histopathology Slide Magnification Improves the Accuracy and Speed of Ovarian Cancer Subtyping

    Jack Breen, Katie Allen, Kieran Zucker, Nicolas M. Orsi, and Nishant Ravikumar

    L3

    Peer-reviewed ISBI 2024 proceedings paper.

    MIL / WSI · WSI engineering · evaluation · magnification ablation · ovarian cancer subtyping · attention MIL · efficiency benchmark · low magnification

    Official artifacts: Author manuscript

    Metadata checked

  211. MIL / WSI · LongMIL · long context · local–global attention

    Metadata checked

  212. self-supervised learning · PathDino · HistoRotate · rotation invariance

    Metadata checked

  213. self-supervised learning · foundation encoder · RudolfV · data curation · tile encoder

    Metadata checked

  214. 2024MICCAIPeer reviewed

    SlideGCD: Slide-based Graph Collaborative Training with Knowledge Distillation for Whole Slide Image Classification

    Tong Shu, Jun Shi, Dongdong Sun, Zhiguo Jiang, and Yushan Zheng

    L3

    knowledge distillation / model transfer · MIL / WSI · whole-slide image · multiple-instance learning · slide graph · online distillation

    Official artifacts: Official code

    Metadata checked

  215. 2024Nature MethodsPeer reviewed

    SpatialData: an open and universal data framework for spatial omics

    Luca Marconato et al.

    L2

    Published online in 2024 and assigned to volume 22 in 2025.

    WSI engineering · spatial / molecular · spatial data model · coordinate systems · interoperability

    Official artifacts: Documentation

    Metadata checked

  216. 2024Nature MedicinePeer reviewed

    Towards a general-purpose foundation model for computational pathology

    Richard J. Chen et al.

    L2–L3

    self-supervised learning · foundation encoder · UNI · DINOv2 · tile encoder

    Metadata checked

  217. evaluation · reporting guideline · clinical prediction model

    Metadata checked

  218. self-supervised learning · foundation encoder · Virchow2 · mixed magnification · DINOv2

    Metadata checked

  219. MIL / WSI · xMIL · explainability · faithfulness

    Metadata checked

  220. 2023WACVPeer reviewed

    A Morphology Focused Diffusion Probabilistic Model for Synthesis of Histopathology Images

    Puria Azadi Moghadam, Sanne Van Dalen, Karina C. Martin, Jochen Lennerz, Stephen Yip, Hossein Farahani, and Ali Bashashati

    L2–L3

    generative / virtual pathology · evaluation · histopathology DDPM · morphology prioritization · genotype conditioning · glioma

    Official artifacts: Author preprint

    Metadata checked

  221. foundation encoder · pathology VLM · PLIP · OpenPath · image–text alignment

    Metadata checked

  222. 2023EUSIPCOPeer reviewed

    Attention to Detail: Inter-Resolution Knowledge Distillation

    Rocío del Amor, Julio Silva-Rodríguez, Adrián Colomer, and Valery Naranjo

    L3

    Peer-reviewed EUSIPCO 2023 proceedings paper, pages 985–989.

    knowledge distillation / model transfer · WSI engineering · cell / tissue modeling · inter-resolution distillation · Grad-CAM · attention transfer · prostate grading · low-resolution deployment

    Official artifacts: Open proceedings paper · Official code

    Metadata checked

  223. self-supervised learning · foundation encoder · benchmark · domain-specific pretraining

    Metadata checked

  224. pathology VLM · biomedical VLM · image-text pretraining · general comparator

    Metadata checked

  225. self-supervised learning · foundation encoder · health-system scale · DINO · MAE

    Metadata checked

  226. 2023IEEE Journal of Biomedical and Health InformaticsPeer reviewed

    Deep Multi-Magnification Similarity Learning for Histopathological Image Classification

    Songhui Diao, Weiren Luo, Jiaxin Hou, Ricardo Lambo, Hamas A. AL-kuhali, Hanqing Zhao, Yinli Tian, Yaoqin Xie, Nazar Zaki, and Wenjian Qin

    L3

    Peer-reviewed journal article 27(3):1535–1545. DMSL learns paired same-field-of-view patch features at two magnifications and retains both magnification branches at inference; its reported comparison metrics are patch-level, not a WSI endpoint.

    cell / tissue modeling · WSI engineering · evaluation · DMSL · same-field-of-view patches · multi-magnification similarity · feature fusion · patch classification

    Official artifacts: PubMed record

    Metadata checked

  227. 2023MICCAIPeer reviewed

    Detecting Domain Shift in Multiple Instance Learning for Digital Pathology Using Fréchet Domain Distance

    Milda Pocevičiūtė, Gabriel Eilertsen, Stina Garvin, and Claes Lundström

    L3

    Peer-reviewed MICCAI 2023 proceedings paper, pages 157–167; its arXiv upload appeared in 2024 and does not change the venue year.

    MIL / WSI · evaluation · Fréchet Domain Distance · domain-shift detection · CLAM · multiple-instance learning · deployment monitoring · robustness / domain shift / privacy

    Official artifacts: MICCAI paper record · Author manuscript

    Metadata checked

  228. 2023NeurIPS Datasets and BenchmarksPeer reviewed

    DiffInfinite: Large Mask-Image Synthesis via Parallel Random Patch Diffusion in Histopathology

    Marco Aversa, Gabriel Nobis, Miriam Hägele, Kai Standvoss, Mihaela Chirica, Roderick Murray-Smith, Ahmed M. Alaa, Lukas Ruff, Daniela Ivanova, Wojciech Samek, Frederick Klauschen, Bruno Sanguinetti, and Luis Oala

    L3

    generative / virtual pathology · cell / tissue modeling · WSI engineering · evaluation · random-patch diffusion · large-image synthesis · semantic masks · pathologist study

    Official artifacts: Author preprint · Official code

    Metadata checked

  229. self-supervised learning · foundation encoder · evaluation · Path Foundation · benchmark · domain-specific optimization

    Metadata checked

  230. self-supervised learning · CluSiam · CluBYOL · cluster constraints

    Official artifacts: Code

    Metadata checked

  231. 2023IEEE Journal of Biomedical and Health InformaticsPeer reviewed

    Knowledge Distillation in Histology Landscape by Multi-Layer Features Supervision

    Sajid Javed, Arif Mahmood, Talha Qaiser, and Naoufel Werghi

    L3

    Peer-reviewed journal article 27(4):2037–2046.

    knowledge distillation / model transfer · cell / tissue modeling · KDTP · multi-layer feature supervision · attention weighting · histology phenotype classification · student compression

    Official artifacts: Open author manuscript

    Metadata checked

  232. 2023Medical Image AnalysisPeer reviewed

    Mitosis domain generalization in histopathology images — The MIDOG challenge

    Marc Aubreville et al.

    L2–L3

    Peer-reviewed Medical Image Analysis article 84:102699; published online 23 November 2022 and assigned to the 2023 volume.

    cell / tissue modeling · evaluation · MIDOG · mitosis detection · domain generalization · scanner shift · containerized benchmark · robustness / domain shift / privacy

    Official artifacts: Author manuscript · Official challenge and data · Reference container

    Metadata checked

  233. spatial / molecular · MOTCat · optimal transport · survival

    Metadata checked

  234. MIL / WSI · MHIM-MIL · hard-instance mining · teacher–student learning · knowledge distillation / model transfer

    Metadata checked

  235. 2023Nature CommunicationsPeer reviewed

    Next-Generation Morphometry for pathomics-data mining in histopathology

    David L. Hölscher et al.

    L2–L3

    cell / tissue modeling · spatial / molecular · pathomics · morphometry · interpretable features

    Metadata checked

  236. cell / tissue modeling · cell detection · tissue context · multi-task learning

    Metadata checked

  237. spatial / molecular · PACpAInt · molecular subtype · intratumour heterogeneity

    Metadata checked

  238. 2023NeurIPS Datasets and BenchmarksPeer reviewed

    Quilt-1M: One Million Image-Text Pairs for Histopathology

    Wisdom Ikezogwo et al.

    L2–L3

    pathology VLM · Quilt-1M · image–text dataset · data provenance

    Metadata checked

  239. cell / tissue modeling · SegPath · restaining · cell type annotation

    Metadata checked

  240. 2023Medical Image AnalysisPeer reviewed

    RetCCL: Clustering-guided contrastive learning for whole-slide image retrieval

    Xiyue Wang et al.

    L2–L3

    self-supervised learning · RetCCL · retrieval · clustering

    Metadata checked

  241. self-supervised learning · foundation encoder · Phikon · iBOT · masked modeling · tile encoder

    Metadata checked

  242. self-supervised learning · I-JEPA · joint-embedding prediction · generative / representation learning · visual representation learning

    Metadata checked

  243. 2023ICCVPeer reviewed

    Sigmoid Loss for Language Image Pre-Training

    Xiaohua Zhai et al.

    L2

    image–text representation · pathology VLM · SigLIP · image–text alignment · detection / segmentation · visual representation learning · multimodal embedding / retrieval · loss / objective design

    Metadata checked

  244. spatial / molecular · BLEEP · spatial transcriptomics · contrastive learning

    Metadata checked

  245. MIL / WSI · S4MIL · state-space model · long sequence

    Metadata checked

  246. 2023NeurIPSPeer reviewed

    Visual Instruction Tuning

    Haotian Liu et al.

    L2–L3

    multimodal LLM · LLaVA · visual instruction tuning · pathology VLM

    Metadata checked

  247. pathology VLM · MI-Zero · zero-shot WSI · vision–language aggregation

    Metadata checked

  248. 2022ICLRPeer reviewed

    BEiT: BERT Pre-Training of Image Transformers

    Hangbo Bao et al.

    Research

    self-supervised learning · BEiT · masked modeling · visual representation learning

    Metadata checked

  249. pathology VLM · CoCa · contrastive captioning · image–text pretraining · image–text representation · captioning / VQA · loss / objective design

    Metadata checked

  250. 2022ECCVPeer reviewed

    ConCL: Concept Contrastive Learning for Dense Prediction Pre-training in Pathology Images

    Jiawei Yang, Hanbo Chen, Yuan Liang, Junzhou Huang, Lei He, and Jianhua Yao

    L2–L3

    self-supervised learning · cell / tissue modeling · concept contrast · dense prediction · segmentation

    Official artifacts: Code

    Metadata checked

  251. 2022ECCVPeer reviewed

    Differentiable Zooming for Multiple Instance Learning on Whole-Slide Images

    Kevin Thandiackal, Boqi Chen, Pushpak Pati, Guillaume Jaume, Drew F. K. Williamson, Maria Gabrani, and Orcun Goksel

    L3

    Peer-reviewed ECCV 2022 proceedings paper.

    MIL / WSI · WSI engineering · ZoomMIL · differentiable zooming · multiresolution selection · whole-slide MIL · evidence acquisition

    Official artifacts: Official code

    Metadata checked

  252. MIL / WSI · DTFD-MIL · pseudo-bags · feature distillation · knowledge distillation / model transfer

    Metadata checked

  253. 2022Medical Image AnalysisPeer reviewed

    Federated learning for computational pathology on gigapixel whole slide images

    Ming Y. Lu, Richard J. Chen, Dehan Kong, Jana Lipkova, Rajendra Singh, Drew F. K. Williamson, Tiffany Y. Chen, and Faisal Mahmood

    L3

    Peer-reviewed Medical Image Analysis article 76:102298; DOI 10.1016/j.media.2021.102298.

    MIL / WSI · HistoFL · federated learning · whole-slide imaging · attention MIL · Gaussian update perturbation · robustness / domain shift / privacy

    Official artifacts: DOI · Author manuscript · Official code

    Metadata checked

  254. 2022CVPRPeer reviewed

    High-Resolution Image Synthesis with Latent Diffusion Models

    Robin Rombach et al.

    L2–L3

    generative / representation learning · latent diffusion · text-to-image · autoencoder · generative vision · multimodal generation / agents · generative / virtual pathology

    Metadata checked

  255. 2022ICLRPeer reviewed

    iBOT: Image BERT Pre-Training with Online Tokenizer

    Jinghao Zhou et al.

    Research

    self-supervised learning · iBOT · masked modeling · self-distillation · visual representation learning

    Metadata checked

  256. 2022Machine Learning for Biomedical ImagingPeer reviewed

    Learning Representations with Contrastive Self-Supervised Learning for Histopathology Applications

    Karin Stacke et al.

    Research

    self-supervised learning · histopathology · contrastive learning · view construction

    Metadata checked

  257. 2022CVPRPeer reviewed

    Masked Autoencoders Are Scalable Vision Learners

    Kaiming He et al.

    L2

    computer vision · self-supervised learning · MAE · masked modeling · generative / representation learning · visual representation learning

    Metadata checked

  258. spatial / molecular · PORPOISE · pan-cancer · multimodal prognosis

    Metadata checked

  259. spatial / molecular · Pathomic Fusion · histology–genomics · multimodal fusion

    Metadata checked

  260. evaluation · DECIDE-AI · early clinical evaluation · reporting guideline

    Metadata checked

  261. self-supervised learning · MIL / WSI · foundation encoder · HIPT · hierarchical representation · gigapixel WSI

    Metadata checked

  262. 2022Machine Learning with ApplicationsPeer reviewed

    Self supervised contrastive learning for digital histopathology

    Ozan Ciga et al.

    Research

    self-supervised learning · histopathology · SimCLR · data scale

    Metadata checked

  263. Research

    self-supervised learning · histopathology · consistency training · semi-supervised learning

    Metadata checked

  264. spatial / molecular · SlideGraph+ · HER2 · graph neural network

    Metadata checked

  265. spatial / molecular · Hist2ST · spatial transcriptomics · graph neural network

    Metadata checked

  266. 2022Communications MedicinePeer reviewed

    TIAToolbox as an End-to-End Library for Advanced Tissue Image Analytics

    Pocock et al.

    L1–L2

    WSI engineering · software · WSI pipeline · reproducibility

    Metadata checked

  267. self-supervised learning · foundation encoder · CTransPath · tile encoder · contrastive learning

    Metadata checked

  268. 2022Archives of Pathology & Laboratory MedicineGuideline

    Validating Whole Slide Imaging Systems for Diagnostic Purposes in Pathology

    Andrew J. Evans et al.

    L3

    Published online in 2021 and in the 2022 journal issue; active CAP evidence-based guideline.

    WSI engineering · evaluation · CAP guideline · WSI validation · diagnostic workflow

    Official artifacts: CAP guideline page

    Metadata checked

  269. 2022ICLRPeer reviewed

    VICReg: Variance-Invariance-Covariance Regularization for Self-Supervised Learning

    Adrien Bardes, Jean Ponce, and Yann LeCun

    Research

    self-supervised learning · VICReg · collapse avoidance · generative / representation learning · visual representation learning

    Metadata checked

  270. Research

    self-supervised learning · Barlow Twins · redundancy reduction · generative / representation learning · visual representation learning

    Metadata checked

  271. 2021Nature MethodsPeer reviewed

    Cellpose: A Generalist Algorithm for Cellular Segmentation

    Stringer et al.

    L2

    cell / tissue modeling · Cellpose · generalist segmentation · flow field

    Metadata checked

  272. 2021Nature Biomedical EngineeringPeer reviewed

    Data-efficient and weakly supervised computational pathology on whole-slide images

    Ming Y. Lu et al.

    L2

    MIL / WSI · CLAM · attention MIL · instance clustering

    Metadata checked

  273. MIL / WSI · DSMIL · critical instance · contrastive features

    Metadata checked

  274. 2021ICCVPeer reviewed

    Emerging Properties in Self-Supervised Vision Transformers

    Mathilde Caron et al.

    L2

    computer vision · self-supervised learning · DINO · self-distillation · vision transformer · generative / representation learning · visual representation learning · knowledge distillation / model transfer

    Metadata checked

  275. 2021CVPRPeer reviewed

    Exploring Simple Siamese Representation Learning

    Xinlei Chen and Kaiming He

    Research

    self-supervised learning · SimSiam · stop-gradient · visual representation learning

    Metadata checked

  276. 2021IEEE Transactions on Medical ImagingPeer reviewed

    Learning Domain-Agnostic Visual Representation for Computational Pathology Using Medically-Irrelevant Style Transfer Augmentation

    Rikiya Yamashita, Jin Long, Snikitha Banda, Jeanne Shen, and Daniel L. Rubin

    L2–L3

    Peer-reviewed journal article in IEEE Transactions on Medical Imaging 40(12):3945–3954; the linked arXiv manuscript is an author version.

    WSI engineering · evaluation · STRAP · style transfer augmentation · domain generalization · stain robustness · CAMELYON17-WILDS · robustness / domain shift / privacy

    Official artifacts: Author manuscript · Official code

    Metadata checked

  277. image–text representation · pathology VLM · CLIP · image–text alignment · zero-shot · detection / segmentation · visual representation learning · multimodal embedding / retrieval · loss / objective design

    Metadata checked

  278. cell / tissue modeling · Lizard · colon nuclei · dataset

    Metadata checked

  279. 2021IEEE Transactions on Medical ImagingPeer reviewed

    MoNuSAC2020: A Multi-Organ Nuclei Segmentation and Classification Challenge

    Verma et al.

    L2

    cell / tissue modeling · MoNuSAC · nuclei classification · challenge

    Metadata checked

  280. spatial / molecular · MCAT · histology–omics fusion · survival

    Metadata checked

  281. 2021Nature MethodsPeer reviewed

    OME-NGFF: a next-generation file format for expanding bioimaging data-access strategies

    Josh Moore, Chris Allan, Sébastien Besson, Jean-Marie Burel, Erin Diel, David Gault, Kevin Kozlowski, Dominik Lindner, Melissa Linkert, Trevor Manz, Will Moore, Constantin Pape, Christian Tischer, and Jason R. Swedlow

    L2–L3

    WSI engineering · OME-NGFF · OME-Zarr · chunked arrays · multiscale bioimaging

    Official artifacts: Version-of-record DOI · Official OME-NGFF specification

    Metadata checked

  282. 2021Artificial Intelligence in MedicinePeer reviewed

    Resolution-Based Distillation for Efficient Histology Image Classification

    Joseph DiPalma, Arief A. Suriawinata, Laura J. Tafe, Lorenzo Torresani, and Saeed Hassanpour

    L3

    Peer-reviewed journal article 119:102136.

    knowledge distillation / model transfer · WSI engineering · self-supervised learning · cell / tissue modeling · cross-resolution distillation · low-magnification histology · feature-map matching · unlabeled transfer set · compute reduction

    Official artifacts: Open-access article · Author manuscript

    Metadata checked

  283. 2021IEEE Transactions on Medical ImagingPeer reviewed

    Self-Path: Self-Supervision for Classification of Pathology Images with Limited Annotations

    Navid Alemi Koohbanani et al.

    Research

    self-supervised learning · histopathology · limited annotations · pretext task

    Metadata checked

  284. Research

    self-supervised learning · histopathology · generative pretext · spatial context

    Metadata checked

  285. 2021NeurIPS LMRL workshop / arXivPreprint

    Self-Supervised Vision Transformers Learn Visual Concepts in Histopathology

    Chen et al.

    Research

    self-supervised learning · histopathology · vision transformer · interpretability

    Metadata checked

  286. WSI engineering · evaluation · site signature · shortcut learning · bias · robustness / domain shift / privacy

    Metadata checked

  287. 2021ACL-IJCNLP Short PapersPeer reviewed

    Towards Visual Question Answering on Pathology Images

    Xuehai He et al.

    L1–L2

    pathology VLM · visual question answering · dataset · benchmark

    Official artifacts: Data and code

    Metadata checked

  288. MIL / WSI · TransMIL · transformer aggregation · spatial context

    Metadata checked

  289. spatial / molecular · Patch-GCN · spatial graph · survival

    Metadata checked

  290. 2021ICMLPeer reviewed

    WILDS: A Benchmark of in-the-Wild Distribution Shifts

    Pang Wei Koh et al.

    L2–L3

    evaluation / reproducibility · WILDS · distribution shift · benchmark · NLP tasks / evaluation · vision evaluation / robustness · robustness / domain shift / privacy

    Metadata checked

  291. L2–L3

    spatial / molecular · HE2RNA · bulk expression · whole-slide image

    Metadata checked

  292. 2020IEEE Transactions on Medical ImagingPeer reviewed

    A Multi-Organ Nucleus Segmentation Challenge

    Kumar et al.

    L2

    cell / tissue modeling · MoNuSeg · nuclei · cross-organ generalization

    Metadata checked

  293. computer vision · self-supervised learning · SimCLR · contrastive learning · generative / representation learning · visual representation learning · loss / objective design

    Metadata checked

  294. evaluation · Gleason grading · observer study · external test

    Metadata checked

  295. 2020NeurIPSPeer reviewed

    Bootstrap Your Own Latent

    Jean-Bastien Grill et al.

    Research

    self-supervised learning · BYOL · self-distillation · generative / representation learning · visual representation learning · knowledge distillation / model transfer

    Metadata checked

  296. 2020NeurIPSPeer reviewed

    Denoising Diffusion Probabilistic Models

    Jonathan Ho, Ajay Jain, and Pieter Abbeel

    L2

    generative / representation learning · diffusion · denoising · score matching · generative vision · generative / virtual pathology

    Metadata checked

  297. 2020ML4H at NeurIPSPeer reviewed

    Evaluation of Contrastive Predictive Coding for Histopathology Applications

    Karin Stacke et al.

    Research

    self-supervised learning · histopathology · CPC · negative result

    Metadata checked

  298. evaluation · SPIRIT-AI · trial protocol · reporting guideline

    Metadata checked

  299. cell / tissue modeling · HoVer-Net · nuclei · instance classification

    Metadata checked

  300. 2020arXivTechnical report

    Improved Baselines with Momentum Contrastive Learning

    Xinlei Chen et al.

    Research

    self-supervised learning · MoCo v2 · contrastive learning · visual representation learning

    Metadata checked

  301. 2020Nature Biomedical EngineeringPeer reviewed

    Integrating Spatial Gene Expression and Breast Tumour Morphology via Deep Learning

    He et al.

    L2–L3

    spatial / molecular · ST-Net · spatial transcriptomics · gene expression

    Metadata checked

  302. Research

    self-supervised learning · MoCo · contrastive learning · generative / representation learning · visual representation learning

    Metadata checked

  303. 2020Medical Image AnalysisPeer reviewed

    NuClick: A Deep Learning Framework for Interactive Segmentation of Microscopic Images

    Alemi Koohbanani et al.

    L2

    cell / tissue modeling · interactive segmentation · annotation efficiency

    Metadata checked

  304. cell / tissue modeling · PanNuke · pan-cancer nuclei · dataset

    Metadata checked

  305. evaluation · CONSORT-AI · clinical trial · reporting guideline

    Metadata checked

  306. 2020arXiv / ML4H extended abstractPreprint

    Self-Supervision Closes the Gap Between Weak and Strong Supervision in Histology

    Ozan Ciga et al.

    Research

    self-supervised learning · histopathology · weak supervision · MoCo v2

    Metadata checked

  307. Research

    self-supervised learning · SwAV · prototypes · clustering · visual representation learning

    Metadata checked

  308. MIL / WSI · evaluation · weak supervision · whole-slide image

    Metadata checked

  309. 2019NeurIPSPeer reviewed

    Deep Leakage from Gradients

    Ligeng Zhu, Zhijian Liu, and Song Han

    L2–L3

    privacy / federated learning · gradient inversion · federated learning · privacy attack · shared gradients · data reconstruction · robustness / domain shift / privacy

    Official artifacts: Final proceedings PDF · Authors' implementation

    Metadata checked

  310. spatial / molecular · MSI · biomarker prediction · external validation

    Metadata checked

  311. 2019JCO Clinical Cancer InformaticsPeer reviewed

    HistoQC: An Open-Source Quality Control Tool for Digital Pathology Slides

    Janowczyk et al.

    L1–L2

    WSI engineering · quality control · artifact · batch effect

    Metadata checked

  312. WSI engineering · stain augmentation · normalization · domain shift · robustness / domain shift / privacy

    Metadata checked

  313. 2019Nature Biomedical EngineeringPeer reviewed

    Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning

    Yair Rivenson, Hongda Wang, Zhensong Wei, Kevin de Haan, Yibo Zhang, Yichen Wu, Harun Günaydın, Jonathan E. Zuckerman, Thomas Chong, Anthony E. Sisk, Lindsey M. Westbrook, W. Dean Wallace, and Aydogan Ozcan

    L3

    generative / virtual pathology · virtual staining · autofluorescence microscopy · histopathology · generative adversarial network

    Metadata checked

  314. 2018ICMLPeer reviewed

    Attention-based Deep Multiple Instance Learning

    Maximilian Ilse, Jakub Tomczak, and Max Welling

    L1–L2

    MIL / WSI · attention MIL · bag aggregation

    Metadata checked

  315. 2018MICCAIPeer reviewed

    Cell Detection with Star-Convex Polygons

    Schmidt et al.

    L2

    cell / tissue modeling · StarDist · instance segmentation · shape representation

    Metadata checked

  316. spatial / molecular · mutation prediction · lung cancer · molecular screening

    Metadata checked

  317. 2018ECCVPeer reviewed

    Deep Clustering for Unsupervised Learning of Visual Features

    Mathilde Caron et al.

    Research

    self-supervised learning · clustering · pseudo-labels · visual representation learning

    Metadata checked

  318. L2–L3

    evaluation · reader study · human–AI assistance · workflow time

    Metadata checked

  319. 2018Journal of Pathology InformaticsPeer reviewed

    Implementing the DICOM Standard for Digital Pathology

    Markus D. Herrmann, David A. Clunie, Andriy Fedorov, Sean W. Doyle, Steven Pieper, Veronica Klepeis, Long P. Le, George L. Mutter, David S. Milstone, Thomas J. Schultz, Ron Kikinis, Gopal K. Kotecha, David H. Hwang, Katherine P. Andriole, A. John Iafrate, James A. Brink, Giles W. Boland, Keith J. Dreyer, Mark Michalski, Jeffrey A. Golden, David N. Louis, and Jochen K. Lennerz

    L2–L3

    WSI engineering · DICOM WSI · interoperability · total pixel matrix · DICOMweb

    Official artifacts: Official DICOM pathology standard portal

    Metadata checked

  320. 2018arXivPreprint

    Representation Learning with Contrastive Predictive Coding

    Aaron van den Oord, Yazhe Li, and Oriol Vinyals

    Research

    self-supervised learning · CPC · InfoNCE · visual representation learning · loss / objective design

    Metadata checked

  321. self-supervised learning · instance discrimination · contrastive learning · visual representation learning

    Metadata checked

  322. 2018ICLRPeer reviewed

    Unsupervised Representation Learning by Predicting Image Rotations

    Spyros Gidaris, Praveer Singh, and Nikos Komodakis

    Research

    self-supervised learning · pretext task · rotation · visual representation learning

    Metadata checked

  323. 2017AISTATSPeer reviewed

    Communication-Efficient Learning of Deep Networks from Decentralized Data

    H. Brendan McMahan, Eider Moore, Daniel Ramage, Seth Hampson, and Blaise Agüera y Arcas

    L2–L3

    privacy / federated learning · neural networks · FedAvg · federated learning · non-IID clients · robustness / domain shift / privacy

    Metadata checked

  324. 2017NeurIPSPeer reviewed

    Deep Sets

    Manzil Zaheer et al.

    L1–L2

    MIL / WSI · set functions · permutation invariance · aggregation

    Metadata checked

  325. evaluation · CAMELYON16 · diagnostic accuracy · pathologist comparison

    Metadata checked

  326. 2017NeurIPSPeer reviewed

    GANs Trained by a Two Time-Scale Update Rule Converge to a Local Nash Equilibrium

    Martin Heusel, Hubert Ramsauer, Thomas Unterthiner, Bernhard Nessler, and Sepp Hochreiter

    L2

    generative / representation learning · evaluation / reproducibility · generative vision · vision evaluation / robustness · Fréchet Inception Distance · GAN evaluation · two time-scale updates · generative / virtual pathology

    Metadata checked

  327. 2017Medical Image AnalysisPeer reviewed

    Gland Segmentation in Colon Histology Images: The GlaS Challenge Contest

    Sirinukunwattana et al.

    L1–L2

    cell / tissue modeling · gland segmentation · challenge · object metrics

    Metadata checked

  328. 2017CVPRPeer reviewed

    Image-to-Image Translation with Conditional Adversarial Networks

    Phillip Isola, Jun-Yan Zhu, Tinghui Zhou, and Alexei A. Efros

    L3

    generative vision · generative / virtual pathology · pix2pix · conditional GAN · paired image translation · PatchGAN

    Official artifacts: Official implementation

    Metadata checked

  329. 2017ACM CCSPeer reviewed

    Practical Secure Aggregation for Privacy-Preserving Machine Learning

    Keith Bonawitz, Vladimir Ivanov, Ben Kreuter, Antonio Marcedone, H. Brendan McMahan, Sarvar Patel, Daniel Ramage, Aaron Segal, and Karn Seth

    L2–L3

    privacy / federated learning · secure aggregation · federated learning · pairwise masking · secret sharing · client dropout · robustness / domain shift / privacy

    Official artifacts: Version-of-record manuscript · DOI

    Metadata checked

  330. 2017Scientific ReportsPeer reviewed

    QuPath: Open Source Software for Digital Pathology Image Analysis

    Bankhead et al.

    L1

    WSI engineering · annotation · image analysis · software

    Metadata checked

  331. 2017ICCVPeer reviewed

    Unpaired Image-to-Image Translation Using Cycle-Consistent Adversarial Networks

    Jun-Yan Zhu, Taesung Park, Phillip Isola, and Alexei A. Efros

    L3

    generative vision · generative / virtual pathology · CycleGAN · unpaired image translation · cycle consistency · adversarial learning

    Official artifacts: Official implementation

    Metadata checked

  332. 2016ACM CCSPeer reviewed

    Deep Learning with Differential Privacy

    Martín Abadi et al.

    L2–L3

    privacy / federated learning · neural networks · DP-SGD · privacy accounting · gradient clipping · robustness / domain shift / privacy

    Official artifacts: Google differential privacy

    Metadata checked

  333. 2016CVPRPeer reviewed

    Deep Residual Learning for Image Recognition

    Kaiming He, Xiangyu Zhang, Shaoqing Ren, and Jian Sun

    L1

    computer vision · foundation encoder · CNN · residual networks · neural networks · image recognition

    Metadata checked

  334. 2016JMLRPeer reviewed

    Domain-Adversarial Training of Neural Networks

    Yaroslav Ganin et al.

    L2

    generative / representation learning · domain adaptation · gradient reversal · invariance · robustness / domain shift / privacy

    Metadata checked

  335. 2016IEEE Transactions on Medical ImagingPeer reviewed

    Structure-Preserving Color Normalization and Sparse Stain Separation for Histological Images

    Vahadane et al.

    L2

    WSI engineering · stain normalization · sparse decomposition · robustness / domain shift / privacy

    Metadata checked

  336. 2016ECCVPeer reviewed

    Unsupervised Learning of Visual Representations by Solving Jigsaw Puzzles

    Mehdi Noroozi and Paolo Favaro

    Research

    self-supervised learning · pretext task · jigsaw · visual representation learning

    Metadata checked

  337. 2015MICCAIPeer reviewed

    U-Net: Convolutional Networks for Biomedical Image Segmentation

    Olaf Ronneberger, Philipp Fischer, and Thomas Brox

    L1–L2

    computer vision · cell / tissue modeling · segmentation · biomedical imaging · detection / segmentation

    Metadata checked

  338. 2015ICCVPeer reviewed

    Unsupervised Visual Representation Learning by Context Prediction

    Carl Doersch, Abhinav Gupta, and Alexei A. Efros

    Research

    self-supervised learning · pretext task · spatial context · visual representation learning

    Metadata checked

  339. 2014NeurIPSPeer reviewed

    Generative Adversarial Nets

    Ian Goodfellow et al.

    L2

    generative / representation learning · GAN · adversarial learning · implicit density · generative vision · generative / virtual pathology

    Metadata checked

  340. 2013Journal of Pathology InformaticsPeer reviewed

    OpenSlide: A Vendor-Neutral Software Foundation for Digital Pathology

    Goode et al.

    L1

    WSI engineering · whole-slide image · interoperability · slide reader

    Metadata checked

  341. WSI engineering · stain normalization · optical density · robustness / domain shift / privacy

    Metadata checked

  342. 1997Artificial IntelligencePeer reviewed

    Solving the Multiple Instance Problem with Axis-Parallel Rectangles

    Thomas G. Dietterich et al.

    L1

    MIL / WSI · classical MIL · bag labels · instance assumptions

    Metadata checked

  1. Start with one dedicated chapter, because its paper order is pedagogical rather than a leaderboard.
  2. Use the filters here to compare adjacent methods by year, evidence state, or research route.
  3. Open My Library, select the same route, and add the papers you intend to read. Your reading status and notes stay only in your browser.
  4. Re-check the linked primary source before making a publication-status, artifact, performance, licensing, or clinical-use claim.

One paper can belong to several routes. MOOZY, for example, belongs to both foundation encoders and MIL/whole-slide learning because it learns slide representations and then aggregates multiple slides into a patient-case representation. It is not classified as a pathology VLM.

This registry is a reviewed research map, not a global ranking. Route order expresses prerequisites and conceptual progression. The project does not rank papers by arXiv recency, citation count, venue prestige, or a single reported metric because those signals do not establish methodological quality or clinical relevance.

The daily arXiv Radar is the discovery layer. A radar hit enters this registry only after identity, scope, evidence state, route fit, and primary links have been checked.

The catalog is appendable through dated data modules under src/data/papers/computational-pathology/. A new audit module can add canonical records or attach an existing paper to another route without duplicating it. See the source repository’s literature maintenance protocol and paper-suggestion issue form before proposing an update.